Esomeprazole
- Generic Name
- Esomeprazole
- Brand Names
- Nexium, Vimovo, Nexium Control
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 119141-88-7
- Unique Ingredient Identifier
- N3PA6559FT
- Background
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison ...
- Indication
Esomeprazole is indicated for the treatment of acid-reflux disorders including healing and maintenance of erosive esophagitis, and symptomatic gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication, prevention of gastrointestinal bleeds with NSAID use, and for the long-term treatment of pathological hypersecretory conditions incl...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Upper Gastrointestinal Hemorrhage, Zollinger-Ellison Syndrome, Acute benign gastric ulcers, Develop NSAID-induced gastric ulcers, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding
- Associated Therapies
- -
A Study in Healthy Men to Test How Esomeprazole Influences the Amount of BI 1819479 in the Blood
- First Posted Date
- 2022-07-20
- Last Posted Date
- 2023-01-26
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 15
- Registration Number
- NCT05467475
- Locations
- 🇩🇪
Humanpharmakologisches Zentrum Biberach, Biberach, Germany
Proton Pump Inhibitors Effects on Dyspepsia During Ramadan Fasting
- First Posted Date
- 2022-03-18
- Last Posted Date
- 2023-05-16
- Lead Sponsor
- University of Monastir
- Target Recruit Count
- 500
- Registration Number
- NCT05287633
- Locations
- 🇹🇳
Emergency department of university hospital Fattouma Bourguiba of Monastir Monastir, Monastir Tunisia, Monastir, Tunisia
Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment
- First Posted Date
- 2022-02-22
- Last Posted Date
- 2022-03-18
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 388
- Registration Number
- NCT05250050
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, Shanghai, China
🇨🇳Huashan Hospital, Fudan University, Shanghai, Shanghai, China
🇨🇳Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China
Helicobacter Pylori Eradication With Probiotics Combined With Triple Therapy Versus Bismuth-containing Quadruple Therapy
- Conditions
- Interventions
- First Posted Date
- 2022-02-11
- Last Posted Date
- 2022-02-11
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 600
- Registration Number
- NCT05237115
- Locations
- 🇨🇳
Xijing Hospital of Digestive Diseases, Xi'an, Shanxi, China
The Evaluation of Triple Therapy With Vonoprazan, Amoxicillin and Bismuth for Eradication of Helicobacter Pylori
- Conditions
- Interventions
- First Posted Date
- 2022-01-12
- Last Posted Date
- 2022-03-22
- Lead Sponsor
- Huazhong University of Science and Technology
- Target Recruit Count
- 672
- Registration Number
- NCT05189444
- Locations
- 🇨🇳
Tongji Hospital, Tongji Medical College, HUST, Wuhan, Hubei, China
A Study to Learn How a Proton Pump Inhibitor Affects the Way Elinzanetant (BAY 3427080) Moves Into, Through and Out of the Body, and How Much of it Gets Absorbed by the Body When Taken as a Single and Small Radioactive Dose in Healthy Adults
- Conditions
- Interventions
- First Posted Date
- 2021-09-29
- Last Posted Date
- 2022-03-17
- Lead Sponsor
- Bayer
- Target Recruit Count
- 14
- Registration Number
- NCT05061563
- Locations
- 🇳🇱
PRAHealthSciences, Groningen, Netherlands
A Multiple Dose Study of LY3502970 in Healthy Participants
- First Posted Date
- 2021-09-21
- Last Posted Date
- 2022-04-26
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 26
- Registration Number
- NCT05051566
- Locations
- 🇬🇧
Quotient Clinical Ltd, Nottingham, United Kingdom
Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France)
- First Posted Date
- 2021-09-09
- Last Posted Date
- 2021-09-09
- Lead Sponsor
- Genuine Research Center, Egypt
- Target Recruit Count
- 30
- Registration Number
- NCT05038969
- Locations
- 🇪🇬
Genuine Research Center GRC, Cairo, Egypt
Efficacy and Safety of Vonoprazan as First-line Treatment for Helicobacter Pylori Eradication
- First Posted Date
- 2021-06-01
- Last Posted Date
- 2021-06-01
- Target Recruit Count
- 234
- Registration Number
- NCT04907747
- Locations
- 🇨🇳
Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China
Rifabutin-containing Triple Therapy for Treatment of Helicobacter Pylori
- Conditions
- Interventions
- First Posted Date
- 2021-05-10
- Last Posted Date
- 2022-11-15
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 413
- Registration Number
- NCT04879992
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Drug Development Updates
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