Hydrocortisone
- Generic Name
- Hydrocortisone
- Brand Names
- Ala-cort, Ala-scalp, Alcortin, Alkindi, Anusol HC, Aquanil HC, Casporyn HC, Cipro, Cipro HC, Colocort, Cortaid, Cortane-B, Cortef, Cortenema, Cortisporin, Cortizone-10, Dermacort, Dermarest Eczema, Dermazene, Home Papkit, Hydroskin, Monistat Itch Relief, Neosporin Eczema, Preparation H Hydrocortisone, Procto-med, Procto-pak, Proctocort, Proctol, Proctosedyl, Proctosol, Proctozone HC, Scalpicin Itch Relief, Texacort, Vanoxide-HC, Xerese, Plenadren, Efmody
- Drug Type
- Small Molecule
- Chemical Formula
- C21H30O5
- CAS Number
- 50-23-7
- Unique Ingredient Identifier
- WI4X0X7BPJ
- Background
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Hydrocortisone was granted FDA approval on 5 August 1952.
- Indication
Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation. Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions. A hydrocortisone enema is indicated fo...
- Associated Conditions
- Acute Gouty Arthritis, Acute Leukemia, Acute Otitis Externa, Adrenal Insufficiency, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Crohn's Disease (CD), Dermatitis, Dermatomyositis (DM), Dermatosis, Drug hypersensitivity reaction, Epicondylitis, Erythroblastopenia, Fissure;Anal, Haemorrhoids, Herpes Labialis, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Infection of the Fenestration Cavity, Infection of the Mastoidectomy Cavity, Iridocyclitis, Iritis, Itching caused by Hemorrhoids, Itching of the Anus, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Lymphomas NEC, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Hemorrhoids, Pemphigus, Posterior Uveitis, Posttraumatic Osteoarthritis, Primary adrenocortical insufficiency, Proctitis, Proteinuria, Pruritis of the skin, Psoriatic Arthritis, Rectal inflammations NEC, Rheumatic heart disease, unspecified, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Skin Diseases, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Tenosynovitis, Acute rheumatic carditis, Anterior eye segment inflammation, Cryptitis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Non-suppurative Thyroiditis, Severe Erythema multiforme, Severe Psoriasis, Subacute Bursitis, Superficial infection of the external auditory canal with inflammation, Symptomatic Sarcoidosis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Septic Shock em Steroids
- First Posted Date
- 2010-01-13
- Last Posted Date
- 2010-01-13
- Lead Sponsor
- Unidade de Terapia Intensiva
- Target Recruit Count
- 160
- Registration Number
- NCT01047670
- Locations
- 🇧🇷
Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande do Sul, Brazil
Ketoconazole and Dexamethasone in Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2009-12-21
- Last Posted Date
- 2020-06-29
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 32
- Registration Number
- NCT01036594
- Locations
- 🇺🇸
University of California, San Francisco, San Francisco, California, United States
Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu
- Conditions
- Interventions
- First Posted Date
- 2009-11-17
- Last Posted Date
- 2014-12-18
- Lead Sponsor
- University of Versailles
- Target Recruit Count
- 40
- Registration Number
- NCT01014364
- Locations
- 🇫🇷
Raymond Poincaré hospital, Garches, France
A Study Comparing LEO 80190 Ointment With Hydrocortisone Ointment, Both Applied Once Daily in the Treatment of Psoriasis Vulgaris on the Face and Intertriginous Areas
- First Posted Date
- 2009-11-04
- Last Posted Date
- 2019-01-15
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 40
- Registration Number
- NCT01007591
- Locations
- 🇫🇷
CHU Saint-Etienne Hôpital NOrd, Saint-Etienne, France
Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2009-08-06
- Last Posted Date
- 2018-09-04
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 11
- Registration Number
- NCT00953576
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Mild Versus Potent Corticosteroids as Treatment for Phimosis in Children
- First Posted Date
- 2009-07-07
- Last Posted Date
- 2015-07-30
- Lead Sponsor
- Chelsea and Westminster NHS Foundation Trust
- Registration Number
- NCT00933023
- Locations
- 🇬🇧
Chelsea and Westminster Hospital, London, United Kingdom
Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG
- Conditions
- Interventions
- Procedure: Autologous peripheral blood stem cells (auto-PBSC) transplantationProcedure: Allogeneic peripheral blood stem cells (allo-PBSC) transplantationDrug: FilgrastimDrug: CyclophosphamideDrug: MelphalanDrug: CyclosporineRadiation: Total lymphoid irradiationBiological: Rabbit anti-thymocyte globulinDrug: Mycophenolate Mofetil 250mgDrug: SolumedrolDrug: DiphenhydramineDrug: AcetaminophenDrug: Hydrocortisone
- First Posted Date
- 2009-05-12
- Last Posted Date
- 2017-10-20
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 9
- Registration Number
- NCT00899847
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Use of Low Dose Ketoconazole in Prostate Cancer That Does Not Respond to Hormone Therapy and Prior Chemotherapy
- First Posted Date
- 2009-05-08
- Last Posted Date
- 2017-03-30
- Lead Sponsor
- University of California, Davis
- Target Recruit Count
- 30
- Registration Number
- NCT00895310
- Locations
- 🇺🇸
University of California, Davis Cancer Center, Sacramento, California, United States
Early Blood Pressure Management in Extremely Premature Infants
- First Posted Date
- 2009-04-02
- Last Posted Date
- 2017-05-25
- Lead Sponsor
- NICHD Neonatal Research Network
- Target Recruit Count
- 10
- Registration Number
- NCT00874393
- Locations
- 🇺🇸
Yale University, New Haven, Connecticut, United States
🇺🇸Wayne State University, Detroit, Michigan, United States
🇺🇸RTI International, Durham, North Carolina, United States
Hydrocortisone Use After Etomidate in Intensive Care
- Conditions
- Interventions
- First Posted Date
- 2009-03-16
- Last Posted Date
- 2010-07-26
- Lead Sponsor
- University Hospital, Grenoble
- Target Recruit Count
- 106
- Registration Number
- NCT00862381
- Locations
- 🇫🇷
Réanimation polyvalente déchocage, centre hospitalier de la région Annecienne, Annecy, France
🇫🇷Pôle d'anesthésie - réanimation, University Hospital of Grenoble, Grenoble, France
Drug Development Updates
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