MedPath

Lebrikizumab

Generic Name
Lebrikizumab
Brand Names
Ebglyss
Drug Type
Biotech
CAS Number
953400-68-5
Unique Ingredient Identifier
U9JLP7V031
Background

Lebrikizumab has been used in trials studying the treatment of Asthma, Allergic Asthma, Atopic Dermatitis, Idiopathic Pulmonary Fibrosis, and COPD, Chronic Obstructive Pulmonary Disease.

A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication

Phase 3
Completed
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2013-06-03
Last Posted Date
2017-05-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1081
Registration Number
NCT01867125
Locations
🇺🇸

Choc Psf, Amc, Orange, California, United States

🇺🇸

North Bay Clinical Trials, Napa, California, United States

🇺🇸

Bensch Research Associates, Stockton, California, United States

and more 227 locations

A Study of Lebrikizumab in Patients Whose Asthma is Uncontrolled With Inhaled Corticosteroids and A Second Controller Medication (LUTE)

Phase 2
Completed
Conditions
Asthma
Interventions
Drug: placebo
First Posted Date
2012-03-06
Last Posted Date
2015-03-05
Lead Sponsor
Genentech, Inc.
Target Recruit Count
258
Registration Number
NCT01545440

A Study of Lebrikizumab in Patients With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and A Second Controller Medication (VERSE)

Phase 2
Completed
Conditions
Asthma
Interventions
Drug: placebo
First Posted Date
2012-03-06
Last Posted Date
2016-11-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
205
Registration Number
NCT01545453

A Study of Lebrikizumab in Healthy Japanese and Caucasian Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: placebo
First Posted Date
2011-08-25
Last Posted Date
2016-11-02
Lead Sponsor
Genentech, Inc.
Target Recruit Count
60
Registration Number
NCT01423318

A Study to Evaluate Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Not Taking Inhaled Corticosteroids

Phase 2
Completed
Conditions
Asthma
Interventions
First Posted Date
2009-09-03
Last Posted Date
2016-11-29
Lead Sponsor
Genentech, Inc.
Target Recruit Count
210
Registration Number
NCT00971035

A Study of Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Inadequately Controlled on Inhaled Corticosteroids

Phase 2
Completed
Conditions
Asthma
Interventions
First Posted Date
2009-06-30
Last Posted Date
2016-11-29
Lead Sponsor
Genentech, Inc.
Target Recruit Count
218
Registration Number
NCT00930163

A Study to Evaluate MILR1444A in the Prevention of Allergen-Induced Airway Obstruction in Adults With Mild Allergic Asthma

Phase 2
Completed
Conditions
Allergic Asthma
Interventions
First Posted Date
2008-10-29
Last Posted Date
2010-05-06
Lead Sponsor
Genentech, Inc.
Target Recruit Count
29
Registration Number
NCT00781443

Safety and Efficacy Study of TNX-650 to Treat Refractory Hodgkin's Lymphoma

Phase 1
Conditions
Hodgkin's Lymphoma
First Posted Date
2007-03-01
Last Posted Date
2008-05-09
Lead Sponsor
Tanox
Target Recruit Count
59
Registration Number
NCT00441818
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

🇺🇸

MD Anderson Cancer Center - Dept. of Lymphoma and Myeloma, Houston, Texas, United States

© Copyright 2025. All Rights Reserved by MedPath