Viiv healthcare co, Glaxosmithkline • For the treatment of HIV infection and chronic hepatitis B (HBV).
Lamivudine is a reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
Lamivudine is a synthetic nucleoside analogue and is phosphorylated intracellularly to its active 5'-triphosphate metabolite, lamivudine triphosphate (L-TP). This nucleoside analogue is incorporated into viral DNA by HIV reverse transcriptase and HBV polymerase, resulting in DNA chain termination.
