Nitric Oxide
- Generic Name
- Nitric Oxide
- Brand Names
- Inomax, Kinox, Noxivent, INOmax
- Drug Type
- Small Molecule
- Chemical Formula
- NO
- CAS Number
- 10102-43-9
- Unique Ingredient Identifier
- 31C4KY9ESH
- Background
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
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- Indication
For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
- Associated Conditions
- Hypoxic Respiratory Failure
- Associated Therapies
- -
Effect of Nitric Oxide (NO) on Ischemic/Reperfusion Injury During Extended Donor Criteria (EDC) Liver Transplantation
- Conditions
- Interventions
- First Posted Date
- 2009-07-29
- Last Posted Date
- 2021-05-28
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 13
- Registration Number
- NCT00948194
- Locations
- 🇺🇸
University of Colorado Hospital, Aurora, Colorado, United States
Phase I Trial of Inhaled Nitric Oxide to Treat Acute Pulmonary Embolism
- First Posted Date
- 2009-02-20
- Last Posted Date
- 2022-04-25
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 25
- Registration Number
- NCT00848731
- Locations
- 🇺🇸
Carolinas Medical Center, Charlotte, North Carolina, United States
Topical Nitric Oxide Trial in Chronic Non-Healing Wounds
- First Posted Date
- 2009-01-15
- Last Posted Date
- 2016-02-26
- Lead Sponsor
- Loma Linda University
- Target Recruit Count
- 7
- Registration Number
- NCT00823095
- Locations
- 🇺🇸
Loma Linda University Medical Center, Loma Linda, California, United States
Clinical Trial on the Reduction of Methicillin Resistant Staphylococcus Aureus (MRSA)
- Conditions
- First Posted Date
- 2008-11-13
- Last Posted Date
- 2011-11-29
- Lead Sponsor
- Nitric BioTherapeutics, Inc
- Target Recruit Count
- 8
- Registration Number
- NCT00790608
- Locations
- 🇬🇧
Department of Wound Healing, Cardiff University, Cardiff, United Kingdom
Reduction of Bacteria in MRSA Positive Ulcers
- First Posted Date
- 2008-10-13
- Last Posted Date
- 2012-01-19
- Lead Sponsor
- Nitric BioTherapeutics, Inc
- Target Recruit Count
- 20
- Registration Number
- NCT00771368
- Locations
- 🇨🇦
Vancouver General Hospital, Vancouver, British Columbia, Canada
Efficacy Study to Evaluate the Effect of Nitric Oxide on the Treatment of Tinea Pedis (Athlete's Foot)
- First Posted Date
- 2008-10-13
- Last Posted Date
- 2010-02-03
- Lead Sponsor
- Nitric BioTherapeutics, Inc
- Target Recruit Count
- 50
- Registration Number
- NCT00771342
- Locations
- 🇨🇦
Vancouver General Hospital, Vancouver, British Columbia, Canada
Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study)
- Conditions
- Interventions
- First Posted Date
- 2008-09-08
- Last Posted Date
- 2013-08-02
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 100
- Registration Number
- NCT00748423
- Locations
- 🇫🇷
Réanimation Médicale, Hôpital A Chenevier-H Mondor, Creteil, France
Inhaled NO as an Anti-inflammatory and Anti-reperfusion Agent in Infants and Children Undergoing Cardiopulmonary Bypass
- First Posted Date
- 2008-01-02
- Last Posted Date
- 2015-11-04
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 17
- Registration Number
- NCT00585013
- Locations
- 🇺🇸
St. Louis Children's Hospital, St. Louis, Missouri, United States
Safety and Efficacy Study of Nitric Oxide in Patients Going Through Lung Transplantation
- First Posted Date
- 2007-12-10
- Last Posted Date
- 2016-10-19
- Lead Sponsor
- Mallinckrodt
- Target Recruit Count
- 49
- Registration Number
- NCT00570245
- Locations
- 🇪🇸
Hospital General La Fe, Valencia, Spain
Nitric Oxide in Myocardial Infarction Size
- Conditions
- Interventions
- First Posted Date
- 2007-12-05
- Last Posted Date
- 2019-11-21
- Lead Sponsor
- Mallinckrodt
- Target Recruit Count
- 29
- Registration Number
- NCT00568061
- Locations
- 🇧🇪
Virga Jesse Hospital, Hasselt, Belgium
🇨🇦University of Alberta Hospital, Edmonton, Alberta, Canada
🇺🇸Northwestern University, Chicago, Illinois, United States
Drug Development Updates
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