Nitric Oxide
- Generic Name
- Nitric Oxide
- Brand Names
- Inomax, Kinox, Noxivent, INOmax
- Drug Type
- Small Molecule
- Chemical Formula
- NO
- CAS Number
- 10102-43-9
- Unique Ingredient Identifier
- 31C4KY9ESH
- Background
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
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- Indication
For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
- Associated Conditions
- Hypoxic Respiratory Failure
- Associated Therapies
- -
Mechanism of Nitric Oxide on Ventilator-induced Diaphragm Dysfunction with Extracorporeal Membrane Lung Assistance
- Conditions
- First Posted Date
- 2024-10-28
- Last Posted Date
- 2024-10-28
- Lead Sponsor
- Zhongnan Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT06660784
- Locations
- 🇨🇳
Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
Perioperative Nitric Oxide Prevents Acute Kidney Injury in Acute Type a Aortic Dissection Patients
- Conditions
- Interventions
- First Posted Date
- 2024-10-02
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- Beijing Anzhen Hospital
- Target Recruit Count
- 216
- Registration Number
- NCT06622291
- Locations
- 🇨🇳
Beijing Anzhen Hospital, Beijing, Beijing, China
Inhaled Nitric Oxide for ARDS-related Pulmonary Hypertension
- Conditions
- Interventions
- First Posted Date
- 2024-02-08
- Last Posted Date
- 2024-02-08
- Lead Sponsor
- Yuri Matusov
- Target Recruit Count
- 20
- Registration Number
- NCT06249633
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
Nitric Oxide Releasing Mouthwash (NORM) for the Management of Oropharyngeal Candidiasis
- First Posted Date
- 2023-11-07
- Last Posted Date
- 2024-07-10
- Lead Sponsor
- Sanotize Research and Development corp.
- Target Recruit Count
- 6
- Registration Number
- NCT06120816
- Locations
- 🇨🇦
Atlantis Dental Cambie, Vancouver, British Columbia, Canada
Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular Function
- Conditions
- Interventions
- First Posted Date
- 2023-10-24
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Fernando Suarez Sipmann
- Target Recruit Count
- 54
- Registration Number
- NCT06097026
- Locations
- 🇪🇸
Fernando Suárez Sipmann, Madrid, Spain
Nitric Oxide Releasing Solution (NORS) For The Treatment Of Human Papillomavirus(HPV) Verrucae Plantaris (Plantar Warts)
- Conditions
- Interventions
- First Posted Date
- 2023-05-26
- Last Posted Date
- 2024-04-17
- Lead Sponsor
- Sanotize Research and Development corp.
- Target Recruit Count
- 20
- Registration Number
- NCT05877313
- Locations
- 🇨🇦
Achilles Foot Health Centre, Surrey, British Columbia, Canada
🇨🇦Pacific Derm, Vancouver, British Columbia, Canada
🇨🇦Spectrum Health, Vancouver, British Columbia, Canada
Prone Positioning vs. Prone Positioning and NO Inhalation in COVID-19 ARDS.
- Conditions
- Interventions
- First Posted Date
- 2023-02-08
- Last Posted Date
- 2023-02-08
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT05715788
- Locations
- 🇨🇳
Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China
Nitric Oxide Nasal Spray (NONS) To Treat and Prevent the Exacerbation of Infection in Individuals With Mild COVID-19
- First Posted Date
- 2022-10-31
- Last Posted Date
- 2022-10-31
- Lead Sponsor
- Sanotize Research and Development corp.
- Target Recruit Count
- 306
- Registration Number
- NCT05599919
- Locations
- 🇮🇳
Aster Prime Hospital, Hyderabad, India
🇮🇳Orchid Specialty Hospital, Lohgaon, India
🇮🇳Bangalore Medical College and Research Institute, Bangalore, India
Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection
- Conditions
- Interventions
- First Posted Date
- 2021-11-05
- Last Posted Date
- 2023-05-06
- Lead Sponsor
- Sanotize Research and Development corp.
- Target Recruit Count
- 1389
- Registration Number
- NCT05109611
- Locations
- 🇱🇰
National Institute of Infectious Diseases Hospital, Angoda, Angoda, Sri Lanka
🇱🇰Puttalam Base Hospital,, Puttalam, Sri Lanka
🇨🇦Medical Trust Clinics , Inc, Oshawa, Ontario, Canada
Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).
- Conditions
- Interventions
- First Posted Date
- 2021-09-22
- Last Posted Date
- 2024-04-03
- Lead Sponsor
- Dr. Denis O'Donnell
- Target Recruit Count
- 40
- Registration Number
- NCT05052229
- Locations
- 🇨🇦
Respiratory Investigation Unit, Kingston General Hospital, Kingston, Ontario, Canada
Drug Development Updates
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