Nitric Oxide
- Generic Name
- Nitric Oxide
- Brand Names
- Inomax, Kinox, Noxivent, INOmax
- Drug Type
- Small Molecule
- Chemical Formula
- NO
- CAS Number
- 10102-43-9
- Unique Ingredient Identifier
- 31C4KY9ESH
- Background
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
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- Indication
For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
- Associated Conditions
- Hypoxic Respiratory Failure
- Associated Therapies
- -
The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in Interstitial Lung Disease.
- First Posted Date
- 2019-11-29
- Last Posted Date
- 2024-05-08
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 40
- Registration Number
- NCT04181359
Nitric Oxide Releasing Sinus Irrigation (NOSi) to Treat Recalcitrant Chronic Rhinosinusitis (RCRS)
- First Posted Date
- 2019-11-15
- Last Posted Date
- 2022-06-30
- Lead Sponsor
- Sanotize Research and Development corp.
- Target Recruit Count
- 56
- Registration Number
- NCT04163978
- Locations
- 🇨🇦
St. Paul's Hospital, Vancouver, British Columbia, Canada
The Effect of Inhaled Nitric Oxide on Deadspace in COPD
- Conditions
- Interventions
- First Posted Date
- 2019-08-28
- Last Posted Date
- 2024-04-03
- Lead Sponsor
- Dr. Denis O'Donnell
- Target Recruit Count
- 13
- Registration Number
- NCT04069052
- Locations
- 🇨🇦
Respiratory Investigation Unit, Kingston General Hospital, Kingston, Ontario, Canada
Evaluation of Two Doses of Nitric Oxide (NO) Given Intermittently Via Inhalation to Subjects With Bronchiolitis
- Conditions
- Interventions
- First Posted Date
- 2019-08-19
- Last Posted Date
- 2020-05-12
- Lead Sponsor
- Beyond Air Inc.
- Target Recruit Count
- 95
- Registration Number
- NCT04060979
- Locations
- 🇮🇱
Haemek Medical Center, Afula, Israel
🇮🇱Soroka Medical Center, Be'er Sheva, Israel
🇮🇱Assuta Ashdod, Ashdod, Israel
Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients
- Conditions
- Interventions
- First Posted Date
- 2019-07-16
- Last Posted Date
- 2022-11-10
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT04022161
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇬🇧MP 825 Southampton General Hospita, Southampton, Hampshire, United Kingdom
Localized Effects of PBM and Exogenous NO on CREST Patients Calcinosis Cutis & Raynaud Phenomenon
- Conditions
- Interventions
- First Posted Date
- 2019-06-03
- Last Posted Date
- 2019-06-03
- Lead Sponsor
- RoseLab Skin Optics Laboratory
- Target Recruit Count
- 5
- Registration Number
- NCT03972566
- Locations
- 🇨🇦
Clinique Dr Daniel Barolet, Laval, Quebec, Canada
Effects of Nitric Oxide on the Endothelium During Hemolysis.
- First Posted Date
- 2018-11-20
- Last Posted Date
- 2022-11-10
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT03748082
- Locations
- 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
🇺🇸Massachusetts General Hospital, Boston, Massachusetts, United States
The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in COPD
- First Posted Date
- 2018-09-20
- Last Posted Date
- 2024-01-11
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 140
- Registration Number
- NCT03679312
- Locations
- 🇨🇦
Clinical Sciences Building, Edmonton, Alberta, Canada
Nitric Oxide During Bypass for Arterial Switch Operation
- Conditions
- Interventions
- First Posted Date
- 2018-09-07
- Last Posted Date
- 2024-04-18
- Lead Sponsor
- Murdoch Childrens Research Institute
- Target Recruit Count
- 300
- Registration Number
- NCT03661385
- Locations
- 🇦🇺
Royal Children's Hospital, Melbourne, Victoria, Australia
🇮🇩Harapan Kita Children and Women's Hospital, Jakarta, Indonesia
🇨🇦Stollery Cildren's Hospital, Edmonton, Alberta, Canada
Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-05-17
- Last Posted Date
- 2020-01-23
- Lead Sponsor
- Nikolay Kamenshchikov
- Target Recruit Count
- 96
- Registration Number
- NCT03527381
Drug Development Updates
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