Nitric Oxide
- Generic Name
- Nitric Oxide
- Brand Names
- Inomax, Kinox, Noxivent, INOmax
- Drug Type
- Small Molecule
- Chemical Formula
- NO
- CAS Number
- 10102-43-9
- Unique Ingredient Identifier
- 31C4KY9ESH
- Background
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
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- Indication
For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
- Associated Conditions
- Hypoxic Respiratory Failure
- Associated Therapies
- -
Safety and Efficacy Study of Nitric Oxide for Inhalation on Chronic Lung Disease in Premature Babies
- First Posted Date
- 2007-10-31
- Last Posted Date
- 2021-02-05
- Lead Sponsor
- Mallinckrodt
- Target Recruit Count
- 800
- Registration Number
- NCT00551642
- Locations
- 🇧🇪
Clinique St. Vincent CHC, Rocourt, Belgium
🇳🇱Beatrix Children's Hospital, University Medical Center Groningen, Groningen, Netherlands
🇮🇹Policlinico S. Orsola, Bologna, Italy
Follow-Up at 6 Years of a Cohort of Children Born Very Prematurely
- First Posted Date
- 2006-10-19
- Last Posted Date
- 2017-03-22
- Lead Sponsor
- Maternite Regionale Universitaire
- Target Recruit Count
- 108
- Registration Number
- NCT00390065
- Locations
- 🇫🇷
Maternite Regionale Universitaire, Nancy, France
🇫🇷CHU Brabois, Vandoeuvre, France
Nitric Oxide Administration for Acute Respiratory Distress Syndrome
- Conditions
- Interventions
- First Posted Date
- 2005-10-18
- Last Posted Date
- 2015-04-24
- Lead Sponsor
- Children's Hospital of Philadelphia
- Target Recruit Count
- 52
- Registration Number
- NCT00240487
- Locations
- 🇺🇸
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome
- Conditions
- Interventions
- First Posted Date
- 2005-09-12
- Last Posted Date
- 2015-10-06
- Lead Sponsor
- Northern State Medical University
- Target Recruit Count
- 28
- Registration Number
- NCT00159510
- Locations
- 🇷🇺
University Hospital #1, Arkhangelsk, Russia, Russian Federation
Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis
- First Posted Date
- 2005-09-02
- Last Posted Date
- 2023-02-23
- Lead Sponsor
- Boston Children's Hospital
- Target Recruit Count
- 18
- Registration Number
- NCT00142051
- Locations
- 🇺🇸
Children's Hospital Boston, Boston, Massachusetts, United States
Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises
- First Posted Date
- 2004-10-28
- Last Posted Date
- 2020-02-05
- Lead Sponsor
- Mallinckrodt
- Target Recruit Count
- 150
- Registration Number
- NCT00094887
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
🇺🇸Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸Colorado Sickle Cell Treatement and Research Center, Aurora, Colorado, United States
The Effects of Nitric Oxide for Inhalation During Left Ventricular Assists Device (LVAD) Implantation
- First Posted Date
- 2003-05-15
- Last Posted Date
- 2016-08-22
- Lead Sponsor
- Mallinckrodt
- Target Recruit Count
- 150
- Registration Number
- NCT00060840
- Locations
- 🇬🇧
Harefield Hospital, Harefield, Middlesex, United Kingdom
🇺🇸Duke University Medical Center, Durham, North Carolina, United States
🇺🇸Cleveland Clinic Foundation, Cleveland, Ohio, United States
Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension
- Conditions
- First Posted Date
- 2001-09-03
- Last Posted Date
- 2019-12-17
- Target Recruit Count
- 59
- Registration Number
- NCT00023296
- Locations
- 🇺🇸
Suburban Hospital, Bethesda, Maryland, United States
🇺🇸National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia
- Conditions
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2008-03-04
- Target Recruit Count
- 58
- Registration Number
- NCT00001716
- Locations
- 🇺🇸
Warren G. Magnuson Clinical Center (CC), Bethesda, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.