Oxytocin
- Generic Name
- Oxytocin
- Brand Names
- Pitocin
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 50-56-6
- Unique Ingredient Identifier
- 1JQS135EYN
- Background
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recog...
- Indication
Administration of exogenous oxytocin is indicated in the antepartum period to initiate or improve uterine contractions for vaginal delivery in situations where there is fetal or maternal concern. For example, It may be used to induce labor in cases of Rh sensitization, maternal diabetes, preeclampsia at or near term, and when delivery is indicated due to pre...
- Associated Conditions
- Incomplete Abortion, Inevitable abortion, Postpartum Bleeding
- Associated Therapies
- Reinforcement of labor
In Vitro Myometrial Contractions in Laboring and Non-laboring Women
- Conditions
- Interventions
- First Posted Date
- 2012-09-21
- Last Posted Date
- 2012-09-21
- Target Recruit Count
- 53
- Registration Number
- NCT01689311
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Carbetocin vs. Oxytocin: In-vitro Myometrial Contractions With and Without Oxytocin Pre-treatment
- First Posted Date
- 2012-09-21
- Last Posted Date
- 2012-09-21
- Target Recruit Count
- 20
- Registration Number
- NCT01689298
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Elective Induction vs Spontaneous Labour in Patients With Heart Disease
- Conditions
- Interventions
- First Posted Date
- 2012-09-03
- Last Posted Date
- 2012-09-03
- Target Recruit Count
- 50
- Registration Number
- NCT01677364
- Locations
- 🇮🇳
Post Graduate Institute of Medical Education and Research, Chandigarh, India
Antipsychotic Effects of Oxytocin
- First Posted Date
- 2012-06-18
- Last Posted Date
- 2019-11-19
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 42
- Registration Number
- NCT01621737
- Locations
- 🇺🇸
University of California, Irvine, Irvine, California, United States
🇺🇸University of California, San Diego, San Diego, California, United States
Premature Rupture of Mambrane and Unfavourable Cervix
- First Posted Date
- 2012-06-08
- Last Posted Date
- 2012-06-08
- Lead Sponsor
- Hillel Yaffe Medical Center
- Target Recruit Count
- 300
- Registration Number
- NCT01615107
- Locations
- 🇮🇱
Hillel Yaffe Medical Center, Hadera, Israel
Effects of Intranasal Oxytocin on Satiety Signaling in People With Schizophrenia
- First Posted Date
- 2012-06-07
- Last Posted Date
- 2019-08-28
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 24
- Registration Number
- NCT01614093
- Locations
- 🇺🇸
Maryland Psychiatric Research Center, Catonsville, Maryland, United States
IV vs IM Oxytocin in the Third Stage of Labor for Prevention of Postpartum Hemorrhage
- First Posted Date
- 2012-05-31
- Last Posted Date
- 2016-03-28
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 653
- Registration Number
- NCT01608958
- Locations
- 🇻🇳
Huong Vuong Hospital, Ho Chi Minh City, Vietnam
🇪🇨Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador
🇹🇷SB Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Turkey
Oxytocin Modulation of Startle Reactivity to Social Stimuli and Moral Decision Making
- First Posted Date
- 2012-05-30
- Last Posted Date
- 2012-05-30
- Lead Sponsor
- University Hospital, Bonn
- Target Recruit Count
- 80
- Registration Number
- NCT01607970
- Locations
- 🇩🇪
Department of Psychiatry, University of Bonn, Bonn, Germany
Oxytocin and Social Cognition
- First Posted Date
- 2012-05-25
- Last Posted Date
- 2014-12-03
- Lead Sponsor
- University Hospital, Bonn
- Target Recruit Count
- 153
- Registration Number
- NCT01606462
- Locations
- 🇩🇪
Department of Psychiatry, University of Bonn, Bonn, Germany
Oxytocin, Carbetocin and Misopristol for Treatment of Postpartum Hemorrhage: A Multicentric Randomized Trial
- Conditions
- Interventions
- First Posted Date
- 2012-05-17
- Last Posted Date
- 2013-05-31
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 300
- Registration Number
- NCT01600612
- Locations
- 🇪🇬
Sohag university, Sohag, Egypt
Drug Development Updates
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