Oxytocin

Generic Name
Oxytocin
Brand Names
Pitocin
Drug Type
Biotech
Chemical Formula
-
CAS Number
50-56-6
Unique Ingredient Identifier
1JQS135EYN
Background

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recog...

Indication

Administration of exogenous oxytocin is indicated in the antepartum period to initiate or improve uterine contractions for vaginal delivery in situations where there is fetal or maternal concern. For example, It may be used to induce labor in cases of Rh sensitization, maternal diabetes, preeclampsia at or near term, and when delivery is indicated due to pre...

Associated Conditions
Incomplete Abortion, Inevitable abortion, Postpartum Bleeding
Associated Therapies
Reinforcement of labor

Oxytocin Administration in the Third Stage of Labour - A Study of Appropriate Route and Dose

Phase 4
Completed
Conditions
Interventions
First Posted Date
2005-09-20
Last Posted Date
2012-11-09
Lead Sponsor
Memorial University of Newfoundland
Target Recruit Count
300
Registration Number
NCT00200252
Locations
🇨🇦

Women's Health Centre, Eastern Health, St. John's, Newfoundland and Labrador, Canada

Optimisation of the Management of Placental Delivery in Second Trimester Pregnancy Interruption

First Posted Date
2005-07-14
Last Posted Date
2009-07-09
Lead Sponsor
The University of Western Australia
Target Recruit Count
251
Registration Number
NCT00120042
Locations
🇦🇺

King Edward Memorial Hospital, Perth, Western Australia, Australia

Misoprostol for the Treatment of Postpartum Hemorrhage

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2005-06-29
Last Posted Date
2009-03-19
Lead Sponsor
Gynuity Health Projects
Target Recruit Count
1786
Registration Number
NCT00116350
Locations
🇹🇷

Ministry of Health Ankara Etlik Maternity and Teaching-Research Hospital, Ankara, Turkey

🇪🇨

Hospital Gineco-Obstetrico Isidro Ayora, Quito, Ecuador

🇧🇫

Centre Hospitalier Universitaire Souro Sanou de Bobo Dioulasso, Bobo Diolasso, Burkina Faso

and more 3 locations
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