Oxytocin
- Generic Name
- Oxytocin
- Brand Names
- Pitocin
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 50-56-6
- Unique Ingredient Identifier
- 1JQS135EYN
- Background
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recog...
- Indication
Administration of exogenous oxytocin is indicated in the antepartum period to initiate or improve uterine contractions for vaginal delivery in situations where there is fetal or maternal concern. For example, It may be used to induce labor in cases of Rh sensitization, maternal diabetes, preeclampsia at or near term, and when delivery is indicated due to pre...
- Associated Conditions
- Incomplete Abortion, Inevitable abortion, Postpartum Bleeding
- Associated Therapies
- Reinforcement of labor
Induction of Labor With Oxytocin: When Should Oxytocin be Held?
- Conditions
- Interventions
- First Posted Date
- 2009-08-12
- Last Posted Date
- 2019-04-23
- Lead Sponsor
- Lehigh Valley Hospital
- Target Recruit Count
- 252
- Registration Number
- NCT00957593
- Locations
- 🇺🇸
Lehigh Valley Health Network, Allentown, Pennsylvania, United States
Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis
- Conditions
- Interventions
- First Posted Date
- 2009-06-12
- Last Posted Date
- 2017-05-23
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 25
- Registration Number
- NCT00919802
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
A Trial of Oral Misoprostol for Labor Augmentation
- First Posted Date
- 2009-05-21
- Last Posted Date
- 2012-11-15
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 350
- Registration Number
- NCT00906347
- Locations
- 🇺🇸
The University of Texas Southwestern Medical Center, Dallas, Texas, United States
Oxytocin to Decrease Blood Loss During Cesarean Section
- First Posted Date
- 2009-05-01
- Last Posted Date
- 2013-03-06
- Lead Sponsor
- American University of Beirut Medical Center
- Target Recruit Count
- 200
- Registration Number
- NCT00891150
- Locations
- 🇱🇧
American University of Beirut Medical Center, Beirut, Lebanon
Intracervical Catheters for Induction of Labour in Women With Prelabour Rupture of Membranes at Term
- Conditions
- Interventions
- First Posted Date
- 2009-04-30
- Last Posted Date
- 2011-07-20
- Lead Sponsor
- McMaster University
- Target Recruit Count
- 5
- Registration Number
- NCT00890630
- Locations
- 🇨🇦
St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada
Oxytocin and Social Cognition in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2009-04-21
- Last Posted Date
- 2019-10-02
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 28
- Registration Number
- NCT00884897
- Locations
- 🇺🇸
Maryland Psychiatric Research Center (MPRC) Outpatient Research Program (ORP); the MPRC Treatment Research Program (TRP), Catonsville, Maryland, United States
Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT
- First Posted Date
- 2008-11-13
- Last Posted Date
- 2016-04-08
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 1798
- Registration Number
- NCT00790062
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
Cardiac Effects of Oxytocin Administrated During Cesarean Section, Signs of Myocardial Ischemia
- First Posted Date
- 2008-10-22
- Last Posted Date
- 2014-03-14
- Lead Sponsor
- Uppsala University
- Target Recruit Count
- 103
- Registration Number
- NCT00777166
- Locations
- 🇸🇪
University hospital Uppsala, Uppsala, Sweden
The Effect of Oxytocin on the Gastric Emptying
- First Posted Date
- 2008-10-21
- Last Posted Date
- 2015-04-07
- Lead Sponsor
- Skane University Hospital
- Target Recruit Count
- 12
- Registration Number
- NCT00776360
Efficacy and Safety Study of Titrated Oral Misoprostol Solution for Labor Augmentation
- First Posted Date
- 2008-06-11
- Last Posted Date
- 2008-07-10
- Lead Sponsor
- China Medical University Hospital
- Target Recruit Count
- 143
- Registration Number
- NCT00695331
- Locations
- 🇨🇳
Labor Unit, Department of Obstetric and Gynecology, China Medical Univertiy Hospital, Taichung, Taiwan
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.