Oxytocin
- Generic Name
- Oxytocin
- Brand Names
- Pitocin
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 50-56-6
- Unique Ingredient Identifier
- 1JQS135EYN
- Background
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recog...
- Indication
Administration of exogenous oxytocin is indicated in the antepartum period to initiate or improve uterine contractions for vaginal delivery in situations where there is fetal or maternal concern. For example, It may be used to induce labor in cases of Rh sensitization, maternal diabetes, preeclampsia at or near term, and when delivery is indicated due to pre...
- Associated Conditions
- Incomplete Abortion, Inevitable abortion, Postpartum Bleeding
- Associated Therapies
- Reinforcement of labor
A Study of Oxytocin in Children and Adolescents With Autistic Disorder
- First Posted Date
- 2011-03-04
- Last Posted Date
- 2017-07-17
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 25
- Registration Number
- NCT01308749
- Locations
- 🇺🇸
University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States
Effects of Intranasal Oxytocin and Vasopressin on Social Behavior
- First Posted Date
- 2011-02-15
- Last Posted Date
- 2011-04-08
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 150
- Registration Number
- NCT01296269
- Locations
- 🇮🇱
Hadassah University Medical Organization, Jerusalem, Israel
Does Intramyometrial Oxytocin Improve Outcome in Elective Cesarean Delivery?
- First Posted Date
- 2010-12-02
- Last Posted Date
- 2012-01-11
- Lead Sponsor
- University of Saskatchewan
- Registration Number
- NCT01252342
- Locations
- 🇨🇦
Royal University Hospital, Saskatoon, Saskatchewan, Canada
"The Effects of Oxytocin on Patients With Borderline Personality Disorder"
- Conditions
- Interventions
- First Posted Date
- 2010-11-18
- Last Posted Date
- 2022-11-03
- Lead Sponsor
- Prof. Dr. Markus Heinrichs
- Target Recruit Count
- 138
- Registration Number
- NCT01243658
- Locations
- 🇩🇪
Albert-Ludwigs-Universität-Freiburg, Freiburg, Baden-Würtemberg, Germany
Oxytocin and Tibolone Adjuncts in Treatment Resistant Depression - A Pilot Study
- Conditions
- Interventions
- First Posted Date
- 2010-11-15
- Last Posted Date
- 2012-01-18
- Lead Sponsor
- The Alfred
- Target Recruit Count
- 15
- Registration Number
- NCT01239888
- Locations
- 🇦🇺
Monash Alfred Psychiatry Research Centre, Melbourne, Victoria, Australia
Oxytocin Add-on for Stable Depressed Patients
- Conditions
- Interventions
- First Posted Date
- 2010-09-29
- Last Posted Date
- 2019-09-25
- Lead Sponsor
- David Feifel
- Target Recruit Count
- 1
- Registration Number
- NCT01211756
- Locations
- 🇺🇸
UCSD Medical Center, San Diego, California, United States
Open Label Comparative Trial of Dinoprostone Plus or Minus Oxytocin Versus Oxytocin Alone in Cervical Ripening for Labor Induction
- Conditions
- Interventions
- First Posted Date
- 2010-08-27
- Last Posted Date
- 2012-08-23
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 170
- Registration Number
- NCT01190163
- Locations
- 🇧🇷
Hospital Maternidade Leonor Mendes de Barros, São Paulo, Brazil
🇧🇷Hospital M Boi Mirim, São Paulo, Brazil
🇧🇷Hospital Municipal Universitário - Faculdade de Medicina do ABC, São Bernardo, São Paulo, Brazil
The Effects of Oxytocin on Complex Social Cognition in Autism Spectrum Disorders
- First Posted Date
- 2010-08-17
- Last Posted Date
- 2021-04-15
- Lead Sponsor
- Alexander Kolevzon
- Target Recruit Count
- 30
- Registration Number
- NCT01183221
- Locations
- 🇺🇸
Mount Sinai School of Medicine - Seaver Autism Center for Research and Treatment, New York, New York, United States
The Effect of Oxytocin on Gastric Emptying
- First Posted Date
- 2010-06-29
- Last Posted Date
- 2015-04-07
- Lead Sponsor
- Skane University Hospital
- Target Recruit Count
- 14
- Registration Number
- NCT01152047
- Locations
- 🇸🇪
Skåne University Hospital, Malmö, Sweden
Cervical Ripening for Induction of Labor: Misoprostol Versus Oxytocin in Conjunction With Foley Balloon
- First Posted Date
- 2010-06-09
- Last Posted Date
- 2018-08-24
- Lead Sponsor
- Aultman Health Foundation
- Target Recruit Count
- 50
- Registration Number
- NCT01139801
- Locations
- 🇺🇸
Aultman Health Foundation, Canton, Ohio, United States
Drug Development Updates
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