Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

Effect-site Concentration of Remifentanil for Smooth Induction With Desflurane

Phase 4
Completed
Conditions
Anesthesia
Interventions
Drug: Remifentanil
Drug: Desflurane
First Posted Date
2015-03-05
Last Posted Date
2020-08-20
Lead Sponsor
Ajou University School of Medicine
Target Recruit Count
26
Registration Number
NCT02379715

Assessment of Hematologic Parameters Before and After Bimaxillary Orthognathic Surgery

Not Applicable
Completed
Conditions
Surgical Blood Loss
Interventions
Drug: Remifentanil
First Posted Date
2015-02-18
Last Posted Date
2015-02-18
Lead Sponsor
Federal University of Minas Gerais
Target Recruit Count
53
Registration Number
NCT02364765
Locations
🇧🇷

Department of Oral and Maxillofacial Surgery - Baleia Hospital, Belo Horizonte, Minas Gerais, Brazil

The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.

First Posted Date
2015-02-02
Last Posted Date
2016-10-26
Lead Sponsor
Murdoch Childrens Research Institute
Target Recruit Count
60
Registration Number
NCT02353182
Locations
🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

🇺🇸

Texas Children's Hospital, Houston, Texas, United States

🇸🇬

KK Women's and Children's Hospital, Singapore, Singapore

and more 3 locations

Remifentanil and Glycemic Response in Cardiac Surgery

First Posted Date
2015-01-28
Last Posted Date
2020-04-21
Lead Sponsor
Kathirvel Subramaniam
Target Recruit Count
116
Registration Number
NCT02349152
Locations
🇺🇸

UPMC Presbyterian Hospital, Pittsburgh, Pennsylvania, United States

Remifentanil for Smooth Emergence in Elderly Patients

Phase 4
Completed
Conditions
Drug Usage
Interventions
Drug: Remifentanil
Drug: Sevoflurane
First Posted Date
2015-01-08
Last Posted Date
2015-12-18
Lead Sponsor
Ajou University School of Medicine
Target Recruit Count
47
Registration Number
NCT02334046
Locations
🇰🇷

Ajou University Hospital, Suwon, Gyeongki-do, Korea, Republic of

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use

First Posted Date
2014-12-04
Last Posted Date
2018-10-17
Lead Sponsor
Norwegian University of Science and Technology
Target Recruit Count
12
Registration Number
NCT02307721
Locations
🇳🇴

Department of Circulation and Medical Imaging, Trondheim, Norway

Effect of Intravenous Infusion of Lidocaine and Remifentanil Perioperatively in Patients Undergoing Mastectomy

Phase 4
Completed
Conditions
Postoperative Pain
Interventions
Drug: Lidocaine
Drug: Remifentanil
First Posted Date
2014-11-14
Last Posted Date
2014-11-25
Lead Sponsor
Hospital de Base
Target Recruit Count
60
Registration Number
NCT02291094

A Phase IV Study Investigating the Effects of Remifentanil Concentrations on Propofol Requirements for Loss of Consciousness, Response to Painful Stimuli, Bispectral Index and Associated Haemodynamic Changes

First Posted Date
2014-11-10
Last Posted Date
2016-03-11
Lead Sponsor
The University of Hong Kong
Target Recruit Count
100
Registration Number
NCT02287181
Locations
🇭🇰

Queen Mary Hospital, Pok Fu Lam, Hong Kong

The Effects of Remifentanil on Attenuating the Hemodynamic Responses After Electroconvulsive Therapy

First Posted Date
2014-10-22
Last Posted Date
2014-10-22
Lead Sponsor
Inonu University
Target Recruit Count
58
Registration Number
NCT02271555
Locations
🇹🇷

Turgut Ozal Medical Center, Malatya, Turkey

Sedation During Noninvasive Ventilation (NIV)

Not Applicable
Conditions
Acute Hypercapnic Respiratory Failure
Interventions
Drug: Remifentanil
First Posted Date
2014-10-15
Last Posted Date
2016-10-11
Lead Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Target Recruit Count
15
Registration Number
NCT02264626
Locations
🇮🇹

San'Orsola Malpighi Hospital, Bologna ITALY, Bologna, Italy

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