Ofloxacin
- Generic Name
- Ofloxacin
- Brand Names
- Ocuflox
- Drug Type
- Small Molecule
- Chemical Formula
- C18H20FN3O4
- CAS Number
- 82419-36-1
- Unique Ingredient Identifier
- A4P49JAZ9H
- Background
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
- Indication
For the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.
- Associated Conditions
- Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Acute Otitis Media (AOM), Bacterial Infections, Cervicitis, Community Acquired Pneumonia (CAP), Complicated Urinary Tract Infection, Conjunctivitis, Epididymitis, Hansen's Disease, Nongonococcal urethritis, Otitis Externa, Prostatitis, Skin and Subcutaneous Tissue Bacterial Infections, Spontaneous Bacterial Peritonitis (SBP), Traveler's Diarrhea, Ulcerative keratitis, Acute Pelvic inflammatory disease, Acute, uncomplicated Gonorrhea, Chronic suppurative Otitis media, Uncomplicated Cystitis
- Associated Therapies
- -
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome
- Conditions
- Interventions
- First Posted Date
- 2022-03-31
- Last Posted Date
- 2024-08-29
- Lead Sponsor
- Central Hospital, Nancy, France
- Target Recruit Count
- 10
- Registration Number
- NCT05302531
- Locations
- 🇫🇷
CHRU Nancy, Vandœuvre-lès-Nancy, Lorraine, France
Ofloxacin Concentration-toxicity Relationship in the Elderly
- Conditions
- First Posted Date
- 2020-08-03
- Last Posted Date
- 2023-03-22
- Lead Sponsor
- Centre Hospitalier Universitaire, Amiens
- Target Recruit Count
- 110
- Registration Number
- NCT04496024
- Locations
- 🇫🇷
CHU Amiens, Amiens, France
Alternative Antibiotic Regimen in Periodontitis Treatment
- Conditions
- Interventions
- First Posted Date
- 2020-04-20
- Last Posted Date
- 2020-04-20
- Lead Sponsor
- Istanbul Medipol University Hospital
- Target Recruit Count
- 74
- Registration Number
- NCT04353362
- Locations
- 🇹🇷
Begum Alkan, Istanbul, Turkey
Pilocarpine After Combined Cataract/Trabectome Surgery
- Conditions
- Interventions
- First Posted Date
- 2019-07-02
- Last Posted Date
- 2022-04-07
- Lead Sponsor
- Montefiore Medical Center
- Registration Number
- NCT04005079
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Pilocarpine Use After Kahook Goniotomy
- First Posted Date
- 2019-05-01
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 142
- Registration Number
- NCT03933631
- Locations
- 🇺🇸
Montefiore Wakefield Campus, Bronx, New York, United States
🇺🇸Montefiore Medical Center, Bronx, New York, United States
VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
- Conditions
- Interventions
- First Posted Date
- 2015-08-19
- Last Posted Date
- 2024-04-23
- Lead Sponsor
- London Vision Clinic
- Target Recruit Count
- 114
- Registration Number
- NCT02528123
- Locations
- 🇬🇧
London Vision Clinic, London, United Kingdom
Antibiotic Treatment for 7 Days Versus 14 Days in Patients With Acute Male Urinary Tract Infection
- Conditions
- Interventions
- First Posted Date
- 2015-04-23
- Last Posted Date
- 2024-05-01
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 274
- Registration Number
- NCT02424461
- Locations
- 🇫🇷
Saint Louis hospital, Paris, France
Descemet Endothelial Thickness Comparison Trial
- First Posted Date
- 2015-02-26
- Last Posted Date
- 2020-11-25
- Lead Sponsor
- Oregon Health and Science University
- Target Recruit Count
- 38
- Registration Number
- NCT02373137
- Locations
- 🇺🇸
Byers Eye Institute, Stanford University, Palo Alto, California, United States
🇺🇸F. I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States
🇺🇸Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States
Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled Trials
- Conditions
- Interventions
- First Posted Date
- 2013-02-26
- Last Posted Date
- 2013-08-28
- Target Recruit Count
- 1303
- Registration Number
- NCT01799356
- Locations
- 🇹🇷
T.C.S.B Mardin Women and Children Hospital, Mardin, Turkey
🇹🇷T.C.S.B. İstanbul Training Research Hospital, Samatya, Fatih, Turkey
🇹🇷T.C.S.B. Kanuni Sultan Suleyman Training Hospital, İstanbul, Kucukcekmece, Turkey
Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin.
- Conditions
- Interventions
- First Posted Date
- 2008-05-26
- Last Posted Date
- 2014-10-15
- Lead Sponsor
- Bayer
- Target Recruit Count
- 749
- Registration Number
- NCT00683865
Drug Development Updates
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