Ofloxacin
- Generic Name
- Ofloxacin
- Brand Names
- Ocuflox
- Drug Type
- Small Molecule
- Chemical Formula
- C18H20FN3O4
- CAS Number
- 82419-36-1
- Unique Ingredient Identifier
- A4P49JAZ9H
- Background
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
- Indication
For the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.
- Associated Conditions
- Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Acute Otitis Media (AOM), Bacterial Infections, Cervicitis, Community Acquired Pneumonia (CAP), Complicated Urinary Tract Infection, Conjunctivitis, Epididymitis, Hansen's Disease, Nongonococcal urethritis, Otitis Externa, Prostatitis, Skin and Subcutaneous Tissue Bacterial Infections, Spontaneous Bacterial Peritonitis (SBP), Traveler's Diarrhea, Ulcerative keratitis, Acute Pelvic inflammatory disease, Acute, uncomplicated Gonorrhea, Chronic suppurative Otitis media, Uncomplicated Cystitis
- Associated Therapies
- -
MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers
- First Posted Date
- 2007-11-26
- Last Posted Date
- 2020-09-03
- Lead Sponsor
- Abeona Therapeutics, Inc
- Target Recruit Count
- 584
- Registration Number
- NCT00563394
- Locations
- 🇺🇸
Seattle VA Medical Center, Seattle, Washington, United States
MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers
- First Posted Date
- 2007-11-26
- Last Posted Date
- 2020-09-03
- Lead Sponsor
- Abeona Therapeutics, Inc
- Target Recruit Count
- 342
- Registration Number
- NCT00563433
- Locations
- 🇺🇸
Seattle VA Medical Center, Seattle, Washington, United States
Ofloxacin vs. Gentamicin as Prophylaxis Prior Transrectal Biopsy of Prostate
- Conditions
- First Posted Date
- 2007-05-30
- Last Posted Date
- 2007-05-30
- Lead Sponsor
- HaEmek Medical Center, Israel
- Target Recruit Count
- 160
- Registration Number
- NCT00480376
- Locations
- 🇮🇱
Urology outpatient clinic, HaEmek MC, Afula, Israel
Antibiotic Therapy in Preventing Early Infection in Patients With Multiple Myeloma Who Are Receiving Chemotherapy
- Conditions
- Interventions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2015-11-11
- Lead Sponsor
- Gary Morrow
- Target Recruit Count
- 212
- Registration Number
- NCT00002850
- Locations
- 🇺🇸
CCOP - Columbus, Columbus, Ohio, United States
🇺🇸St. Mary's Hospital Medical Center - Green Bay, Green Bay, Wisconsin, United States
🇺🇸Siouxland Hematology-Oncology Associates, LLP, Sioux City, Iowa, United States
Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
- Conditions
- Interventions
- Drug: darunavir/ritonavir dosage #1Drug: TAF w/cobicistatDrug: TAF w/cobicistat or ritonavirDrug: tenofovir alafenamide fumarate (TAF)Drug: elvitegravir/cobicistatDrug: darunavir/cobicistatDrug: atazanavir/cobicistatDrug: lopinavir/ritonavir dosage #1Drug: atazanavir/ritonavir/tenofovir dosage #1Drug: lopinavir/ritonavir dosage #2Drug: indinavir/ritonavir dosage #1Drug: fosamprenavir/ritonavirDrug: atazanavir/ritonavir dosage #1Drug: didanosine delayed release (Videx® EC)Drug: emtricitabineDrug: nelfinavir dosage #1Drug: tipranavir/ritonavirDrug: etravirineDrug: darunavir/ritonavir dosage #4Drug: indinavir/ritonavir dosage #2Drug: rilpivirineDrug: ethambutolDrug: efavirenzDrug: raltegravirDrug: dolutegravirDrug: kanamycinDrug: nevirapineDrug: amprenavirDrug: abacavirDrug: tenofovirDrug: maravirocDrug: darunavir/ritonavir dosage #2Drug: lopinavir/ritonavir dosage #3Drug: lopinavir/ritonavir dosage #4Drug: tenofovir/atazanavir/ritonavir dosage #2Drug: atazanavir/ritonavir dosage #2Drug: nelfinavir dosage #2Drug: rifampicinDrug: amikacinDrug: darunavir/ritonavir dosage #3Drug: etonogestrel implantDrug: capreomycinDrug: ethinyl estradiolDrug: isoniazidDrug: moxifloxacinDrug: levoflaxacinDrug: pyrazinamideDrug: ofloxacinDrug: ethionamide/prothionamideDrug: terizidone/cycloserineDrug: para-aminosalicylic acid (PAS)Drug: high dose INHDrug: bedaquilineDrug: clofazamineDrug: delamanidDrug: linezolidDrug: pretomanid
- First Posted Date
- 2002-08-01
- Last Posted Date
- 2022-07-22
- Target Recruit Count
- 1578
- Registration Number
- NCT00042289
- Locations
- 🇺🇸
Usc La Nichd Crs, Los Angeles, California, United States
🇿🇦Wits RHI Shandukani Research Centre CRS, Johannesburg, Gauteng, South Africa
🇺🇸Boston Medical Center Ped. HIV Program NICHD CRS, Boston, Massachusetts, United States
Drug Development Updates
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