Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
- Associated Therapies
- -
The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine
- Conditions
- Interventions
- First Posted Date
- 2012-07-31
- Last Posted Date
- 2016-12-29
- Lead Sponsor
- The Cleveland Clinic
- Registration Number
- NCT01653522
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Study of Lyme Neuroborreliosis
- First Posted Date
- 2012-07-09
- Last Posted Date
- 2019-05-13
- Lead Sponsor
- Turku University Hospital
- Target Recruit Count
- 210
- Registration Number
- NCT01635530
- Locations
- 🇫🇮
Turku University Hospital, Turku, Finland
🇫🇮Helsinki University Hospital, Helsinki, Finland
Effects of Treatments on Atopic Dermatitis
- First Posted Date
- 2012-06-29
- Last Posted Date
- 2024-12-17
- Target Recruit Count
- 130
- Registration Number
- NCT01631617
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)
- First Posted Date
- 2012-05-09
- Last Posted Date
- 2019-02-26
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 29
- Registration Number
- NCT01594827
- Locations
- 🇺🇸
Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
🇺🇸Rainbow Babies and Children's Hospital, Cleveland, Ohio, United States
Doxycycline, Temozolomide and Ipilimumab in Melanoma
- First Posted Date
- 2012-05-02
- Last Posted Date
- 2020-09-02
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 12
- Registration Number
- NCT01590082
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome
- Conditions
- Interventions
- First Posted Date
- 2012-01-25
- Last Posted Date
- 2012-01-25
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 544
- Registration Number
- NCT01518192
- Locations
- 🇸🇮
Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia
🇸🇮Department of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia, Ljubljana, Slovenia
Doxycycline in Therapy of Erythema Migrans
- First Posted Date
- 2011-11-21
- Last Posted Date
- 2016-03-24
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 400
- Registration Number
- NCT01475708
- Locations
- 🇸🇮
UMC Ljubljana, Department of Infectious Diseases, Ljubljana, Slovenia
Oral Contraceptives and Subantimicrobial Doxycycline: Effect on Endometrial Matrix Metalloproteinases
- First Posted Date
- 2011-11-10
- Last Posted Date
- 2020-12-17
- Lead Sponsor
- University of Hawaii
- Target Recruit Count
- 20
- Registration Number
- NCT01469585
- Locations
- 🇺🇸
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, United States
Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PRO
- Conditions
- Interventions
- First Posted Date
- 2011-11-06
- Last Posted Date
- 2019-01-09
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 236
- Registration Number
- NCT01465802
- Locations
- 🇺🇸
City of Hope, Duarte, California, United States
🇺🇸St. Jude Heritage Healthcare, Fullerton, California, United States
🇺🇸UC San Diego Medical Center - La Jolla, La Jolla, California, United States
Randomized Controlled Trial of Standard Versus Systemic Decolonization Therapy for the Eradication of Methicillin-resistant Staphylococcus Aureus (MRSA) Colonization
- Conditions
- Interventions
- First Posted Date
- 2011-09-22
- Last Posted Date
- 2020-02-17
- Lead Sponsor
- Horizon Health Network
- Target Recruit Count
- 100
- Registration Number
- NCT01438515
- Locations
- 🇨🇦
Saint John Regional Hospital, Saint John, New Brunswick, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.