Doxycycline

Generic Name
Doxycycline
Brand Names
Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
Drug Type
Small Molecule
Chemical Formula
C22H24N2O8
CAS Number
564-25-0
Unique Ingredient Identifier
334895S862
Background

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is...

Indication

Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:

It is also used to treat infections caused by the following gram-negative microorganisms:

Associated Conditions
Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
Associated Therapies
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Evaluation of Relapse, Efficacy and Safety of Long-term Treatment With Oracea® vs Placebo

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-08-31
Last Posted Date
2022-08-01
Lead Sponsor
Galderma R&D
Target Recruit Count
235
Registration Number
NCT01426269
Locations
🇺🇸

ATS Clinical Research, Santa Monica, California, United States

🇺🇸

Melissa L. F. Knuckles M.D., P.S.C., Richmond, Kentucky, United States

🇺🇸

Dadeland Dermatology, Coral Gables, Florida, United States

and more 7 locations

Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population

First Posted Date
2011-08-08
Last Posted Date
2020-09-25
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
40
Registration Number
NCT01411202
Locations
🇨🇦

The Ottawa Hospital, Ottawa, Ontario, Canada

🇨🇦

Ottawa Hospital, Ottawa, Ontario, Canada

Development of an Optimal Antibiotic Regime for Long-term Therapy in Stable Chronic Obstructive Pulmonary Disease (COPD)

First Posted Date
2011-07-20
Last Posted Date
2012-06-01
Lead Sponsor
University College, London
Target Recruit Count
200
Registration Number
NCT01398072
Locations
🇬🇧

Academic Unit of Respiratory Medicine, Royal Free Hospital, London, United Kingdom

Examination of the Anti-inflammatory and Insulin Sensitizing Properties of Doxycycline in Humans

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-06-17
Last Posted Date
2020-01-13
Lead Sponsor
University of California, San Diego
Target Recruit Count
39
Registration Number
NCT01375491
Locations
🇺🇸

University of California San Diego Clinical trials Research Institute, La Jolla, California, United States

Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice

First Posted Date
2011-06-07
Last Posted Date
2014-12-12
Lead Sponsor
Morten Lindbaek
Target Recruit Count
225
Registration Number
NCT01368341
Locations
🇳🇴

Antibiotic Centre for Primary Care, University of Oslo, Oslo, Norway

Doxycycline Effects on Inflammation in Cystic Fibrosis

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-03-25
Last Posted Date
2017-03-30
Lead Sponsor
University of Southern California
Target Recruit Count
21
Registration Number
NCT01323101
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

The Qure Study: Q-fever Fatigue Syndrome - Response to Treatment

First Posted Date
2011-03-18
Last Posted Date
2021-06-23
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
156
Registration Number
NCT01318356
Locations
🇳🇱

Radboud university medical center, Nijmegen, Gelderland, Netherlands

Pre-emptive Cycline Treatment on Cetuximab Induced Skin Toxicity in Colorectal Cancer

First Posted Date
2011-03-17
Last Posted Date
2020-03-25
Lead Sponsor
Institut Cancerologie de l'Ouest
Target Recruit Count
25
Registration Number
NCT01317433
Locations
🇫🇷

ICO Paul Papin, Angers, France

🇫🇷

CHU Jean Minjoz, Besançon, France

🇫🇷

Centre Hospitalier Départemental Les Oudairies, La Roche Sur Yon, France

and more 2 locations

Evaluation of Rosacea-related Inflammatory Biochemical Markers in Adult Skin When Treated With Oracea® vs Placebo

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-03-04
Last Posted Date
2022-08-01
Lead Sponsor
Galderma R&D
Target Recruit Count
170
Registration Number
NCT01308619
Locations
🇺🇸

Michigan Center for Research Corp, Clinton Township, Michigan, United States

🇺🇸

Burke Pharmaceutical Research, Hot Springs, Arkansas, United States

🇺🇸

Oregon Medical Research Center, PC, Portland, Oregon, United States

and more 7 locations

A Novel Combination Oral Agent to Treat Acne Vulgaris

First Posted Date
2011-02-23
Last Posted Date
2011-02-23
Lead Sponsor
Nexgen Dermatologics, Inc.
Target Recruit Count
60
Registration Number
NCT01301586
Locations
🇺🇸

Berlin Center, Boynton Beach, Florida, United States

🇺🇸

Palos Verdes Dermatology Associates, Rolling Hills Estates, California, United States

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