Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is...
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
- Associated Therapies
- -
Doxycycline In Lymphangioleiomyomatosis (LAM)
- Conditions
- Interventions
- First Posted Date
- 2009-10-05
- Last Posted Date
- 2015-12-02
- Lead Sponsor
- University of Nottingham
- Target Recruit Count
- 24
- Registration Number
- NCT00989742
- Locations
- 🇬🇧
Nottingham University Hospitals, Nottingham, United Kingdom
Treatment Failure of Chlamydial Infection in Males and Females in Youth Correctional Facilities
- First Posted Date
- 2009-09-18
- Last Posted Date
- 2015-03-18
- Target Recruit Count
- 567
- Registration Number
- NCT00980148
- Locations
- 🇺🇸
University of Alabama Hospital - Infectious Diseases, Birmingham, Alabama, United States
🇺🇸Los Angeles County Department of Public Health - Sexually Transmitted Disease Program, Los Angeles, California, United States
Antibiotics in Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- Interventions
- First Posted Date
- 2009-08-06
- Last Posted Date
- 2010-08-11
- Lead Sponsor
- Odense University Hospital
- Target Recruit Count
- 140
- Registration Number
- NCT00952861
- Locations
- 🇩🇰
Odense University Hospital, Odense, Denmark
Doxycycline and Ceftriaxone in Suspected Early Lyme Neuroborreliosis
- Conditions
- Interventions
- First Posted Date
- 2009-07-20
- Last Posted Date
- 2009-07-20
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 200
- Registration Number
- NCT00942006
- Locations
- 🇸🇮
UMC Ljubljana, Department of Infectious Diseases, Ljubljana, Slovenia
Duration of Antibiotic Treatment of Erythema Migrans
- Conditions
- Interventions
- First Posted Date
- 2009-06-01
- Last Posted Date
- 2017-06-02
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 306
- Registration Number
- NCT00910715
- Locations
- 🇸🇮
UMC Ljubljana, Department of Infectious Diseases, Ljubljana, Slovenia
Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- Interventions
- First Posted Date
- 2009-03-06
- Last Posted Date
- 2009-03-06
- Lead Sponsor
- Medical Center Alkmaar
- Target Recruit Count
- 30
- Registration Number
- NCT00857038
- Locations
- 🇳🇱
Medical Center Alkmaar, Alkmaar, Noord-Holland, Netherlands
Erlotinib Pharmacokinetics During Doxycycline Treatment for Erlotinib-induced Rash
- Conditions
- First Posted Date
- 2008-12-08
- Last Posted Date
- 2015-02-26
- Lead Sponsor
- Northwestern University
- Registration Number
- NCT00803842
Lipids of the Human Tear Film and Their Effect on Tear Stability
- First Posted Date
- 2008-12-05
- Last Posted Date
- 2017-12-22
- Lead Sponsor
- University of Louisville
- Target Recruit Count
- 31
- Registration Number
- NCT00803452
- Locations
- 🇺🇸
Kentucky Lions Eye Center, Louisville, Kentucky, United States
Safety Study of Topical Doxycycline Gel for Adult Diabetic Lower Extremity Ulcers
- First Posted Date
- 2008-10-02
- Last Posted Date
- 2017-04-07
- Lead Sponsor
- NanoSHIFT LLC
- Target Recruit Count
- 15
- Registration Number
- NCT00764361
- Locations
- 🇺🇸
North Florida / South Georgia Veterans Administration Hospital, Gainesville, Florida, United States
A Pilot Study of Inflammatory Markers in Alzheimer's Disease
- First Posted Date
- 2008-07-15
- Last Posted Date
- 2009-02-04
- Lead Sponsor
- McMaster University
- Target Recruit Count
- 21
- Registration Number
- NCT00715858
- Locations
- 🇨🇦
St.Peter's Hospital, Hamilton, Ontario, Canada
Drug Development Updates
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