Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is...
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
- Associated Therapies
- -
Effects of Doxycycline and Rifampicin on Biomarkers of Alzheimer's Disease in the Cerebrospinal Fluid
- Conditions
- Interventions
- First Posted Date
- 2007-02-23
- Last Posted Date
- 2018-03-19
- Lead Sponsor
- Hamilton Health Sciences Corporation
- Target Recruit Count
- 100
- Registration Number
- NCT00439166
- Locations
- 🇨🇦
St.Peter's Hospital, Hamilton, Ontario, Canada
the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris
- First Posted Date
- 2007-01-09
- Last Posted Date
- 2008-01-29
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Target Recruit Count
- 100
- Registration Number
- NCT00419848
- Locations
- 🇮🇷
Shaheed Beheshti Medical University, Skin research center, Tehran, Iran, Islamic Republic of
The Effect of Doxycycline 100mg and Doxycycline 20mg in Treatment of Mild and Moderate Acne
- Conditions
- First Posted Date
- 2006-10-17
- Last Posted Date
- 2008-01-23
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Target Recruit Count
- 100
- Registration Number
- NCT00388778
- Locations
- 🇮🇷
Skin Research Center, Shaheed Beheshti Medical University, Tehran, Iran, Islamic Republic of
Mycoplasma Genitalium Antibiotic Susceptibility and Treatment (MEGA)
- First Posted Date
- 2006-07-31
- Last Posted Date
- 2018-08-15
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 606
- Registration Number
- NCT00358462
- Locations
- 🇺🇸
Public Health -- Seattle & King County Sexually Transmitted Diseases Clinic located at Harborview Medical Center, Seattle, Washington, United States
Antibiotics for the Treatment of Ulcerative Colitis
- Conditions
- First Posted Date
- 2006-07-24
- Last Posted Date
- 2009-02-11
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 40
- Registration Number
- NCT00355602
- Locations
- 🇬🇧
Ninewells Hospital and Medical School, Dundee, Angus, United Kingdom
A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity
- Conditions
- Interventions
- First Posted Date
- 2006-07-17
- Last Posted Date
- 2024-12-19
- Target Recruit Count
- 62
- Registration Number
- NCT00353158
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Controlled Trial: 5-day Course of Telithromycin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus
- Conditions
- First Posted Date
- 2006-07-12
- Last Posted Date
- 2019-02-08
- Lead Sponsor
- Dong-Min Kim
- Target Recruit Count
- 92
- Registration Number
- NCT00351182
- Locations
- 🇰🇷
Chosun University Hospital, Gwangju, Jeonnam, Korea, Republic of
Doxycycline to Treat Mansonella Perstans Infection in Patients With and Without Lymphatic Filariasis
- Conditions
- First Posted Date
- 2006-06-21
- Last Posted Date
- 2017-07-02
- Target Recruit Count
- 1500
- Registration Number
- NCT00340691
- Locations
- 🇺🇸
National Institute of Allergy and Infectious Diseases (NIAID), 9000 Rockville Pi, Bethesda, Maryland, United States
NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)
- Conditions
- Interventions
- First Posted Date
- 2006-05-08
- Last Posted Date
- 2019-03-01
- Target Recruit Count
- 305
- Registration Number
- NCT00322465
- Locations
- 🇺🇸
Delgado Personal Health Center, New Orleans, Louisiana, United States
🇺🇸University of Alabama Hospital - Infectious Diseases, Birmingham, Alabama, United States
🇺🇸University of North Carolina School of Medicine - Center for Infectious Diseases, Chapel Hill, North Carolina, United States
Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting
- Conditions
- Interventions
- First Posted Date
- 2005-10-30
- Last Posted Date
- 2017-12-15
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 56
- Registration Number
- NCT00246740
- Locations
- 🇨🇦
University of Alberta Hospital, Edmonton, Alberta, Canada
Drug Development Updates
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