MedPath

Golcadomide

Generic Name
Golcadomide
Drug Type
Small Molecule
Chemical Formula
C28H30FN5O5
CAS Number
2379572-34-4
Unique Ingredient Identifier
29HLR8Z5BR

A Study to Assess the Safety, Tolerability, Efficacy, and Drug Levels of BMS-986369 (Golcadomide) in Participants With Relapsed or Refractory T-cell Lymphomas in Japan (GOLSEEK-3)

Phase 1
Recruiting
Conditions
Relapsed or Refractory T-cell Lymphomas
Interventions
First Posted Date
2023-09-13
Last Posted Date
2025-05-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
85
Registration Number
NCT06035497
Locations
🇯🇵

Anjo Kosei Hospital, Anjo-shi, Aichi, Japan

🇯🇵

Nagoya City University Hospital, Nagoya, Aichi, Japan

🇯🇵

Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan

and more 37 locations

Treatment of Newly-diagnosed Follicular Lymphoma with CELMoD Golcadomide, Rituximab +/- Nivolumab.

Phase 2
Recruiting
Conditions
Follicular Lymphoma Stage III
Follicular Lymphoma Stage IV
Follicular Lymphoma Stage II
Interventions
First Posted Date
2023-03-28
Last Posted Date
2025-03-21
Lead Sponsor
Olivia Newton-John Cancer Research Institute
Target Recruit Count
40
Registration Number
NCT05788081
Locations
🇦🇺

Grampians Health, Ballarat, Victoria, Australia

🇦🇺

Eastern Health, Box Hill, Victoria, Australia

🇦🇺

University Hospital Geelong, Barwon Health, Geelong, Victoria, Australia

and more 2 locations

A Study to Evaluate the Metabolism and Excretion of BMS-986369 in Healthy Male Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2022-10-05
Last Posted Date
2023-02-17
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
8
Registration Number
NCT05567510
Locations
🇺🇸

Labcorp Clinical Research Unit - Madison, Madison, Wisconsin, United States

A Study to Evaluate the Drug Exposure of Single Ascending Doses of BMS-986369 and the Effect of Food on the BMS-986369 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2022-04-28
Last Posted Date
2024-07-05
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
68
Registration Number
NCT05350800
Locations
🇺🇸

Local Institution - 0001, Miami, Florida, United States

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

First Posted Date
2022-03-17
Last Posted Date
2025-03-04
Lead Sponsor
Genmab
Target Recruit Count
394
Registration Number
NCT05283720
Locations
🇪🇸

Hospital Universitario 12 de Octubre /ID# 243262, Madrid, Spain

🇭🇺

Debreceni Egyetem-Klinikai Kozpont /ID# 242450, Debrecen, Hajdu-Bihar, Hungary

🇭🇺

Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 245935, Kaposvár, Somogy, Hungary

and more 71 locations

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

First Posted Date
2021-12-27
Last Posted Date
2025-05-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
121
Registration Number
NCT05169515
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

🇮🇱

Hadassah Medical Center, Jerusalem, Israel

🇮🇱

Sourasky Medical Center, Tel-Aviv, Israel

and more 23 locations

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

First Posted Date
2021-05-12
Last Posted Date
2025-03-24
Lead Sponsor
Celgene
Target Recruit Count
174
Registration Number
NCT04884035
Locations
🇬🇷

Local Institution - 703, Patras, Greece

🇨🇳

Taichung Veterans General Hospital, Taichung City, Taiwan

🇺🇸

Mayo Clinic - Arizona, Scottsdale, Arizona, United States

and more 31 locations

A Safety and Preliminary Efficacy Study of CC-99282 in Combination With Obinutuzumab in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Phase 1
Completed
Conditions
Lymphoma, Non-Hodgkin
Interventions
First Posted Date
2020-06-16
Last Posted Date
2024-07-25
Lead Sponsor
Celgene
Target Recruit Count
16
Registration Number
NCT04434196
Locations
🇺🇸

Local Institution - 104, Columbus, Ohio, United States

🇺🇸

Local Institution - 106, Boston, Massachusetts, United States

🇺🇸

Local Institution - 101, Portland, Oregon, United States

and more 12 locations

A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)

Phase 1
Recruiting
Conditions
Lymphoma, Non-Hodgkin
Interventions
First Posted Date
2019-04-29
Last Posted Date
2025-02-19
Lead Sponsor
Celgene
Target Recruit Count
438
Registration Number
NCT03930953
Locations
🇺🇸

Local Institution - 114, Los Angeles, California, United States

🇩🇰

Rigshospitalet University Hospital, Copenhagen, Denmark

🇩🇰

Local Institution - 603, Vejle, Denmark

and more 87 locations

A Safety and Efficacy Trial of JCAR017 Combinations in Subjects With Relapsed/Refractory B-cell Malignancies

Phase 1
Completed
Conditions
Lymphoma, Non-Hodgkin
Lymphoma, Large B-Cell, Diffuse
Lymphoma, Follicular
Interventions
First Posted Date
2017-10-16
Last Posted Date
2024-04-04
Lead Sponsor
Celgene
Target Recruit Count
62
Registration Number
NCT03310619
Locations
🇺🇸

Local Institution - 015, Omaha, Nebraska, United States

🇺🇸

Local Institution - 016, Philadelphia, Pennsylvania, United States

🇺🇸

Local Institution - 011, Duarte, California, United States

and more 6 locations
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