Coenzyme Q10

Generic Name
Coenzyme Q10
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C59H90O4
CAS Number
303-98-0
Unique Ingredient Identifier
EJ27X76M46
Background

Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is the coenzyme destined for ...

Indication

The diet supplements containing ubidecarenone are indicated, as stated in the product label, to assist individuals with cardiovascular complaints including congestive heart failure and systolic hypertension. In the product, ubidecarenone is used to increase the cardiac input as well as for the prevention of several other diseases like Parkinson, fibromyalgia...

Associated Conditions
Migraine
Associated Therapies
-

Study About Safety and Efficacy of Coenzyme Q10 in Progressive Supranuclear Palsy

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-05-24
Last Posted Date
2020-01-10
Lead Sponsor
German Parkinson Study Group (GPS)
Target Recruit Count
20
Registration Number
NCT00328874
Locations
🇩🇪

Neurologische Klinik der Philipps-Universität Marburg, Marburg, Hessen, Germany

Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder

Phase 2
Withdrawn
Conditions
First Posted Date
2006-05-19
Last Posted Date
2011-11-23
Lead Sponsor
National Institute of Mental Health (NIMH)
Registration Number
NCT00327756
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Clinical Trial of High Dose CoQ10 in ALS

First Posted Date
2005-10-25
Last Posted Date
2024-05-07
Lead Sponsor
Columbia University
Target Recruit Count
185
Registration Number
NCT00243932
Locations
🇺🇸

Columbia Presbyterian Medical Center, The Neurological Institute, New York, New York, United States

🇺🇸

Washington University in St. Louis School of Medicine, Department of Neurology, Saint Louis, Missouri, United States

🇺🇸

University of Kentucky, Dept of Neurology, College of Medicine, Lexington, Kentucky, United States

and more 16 locations

NINDS Parkinson's Disease Neuroprotection Trial of CoQ10 and GPI 1485

Phase 2
Completed
Conditions
First Posted Date
2004-01-27
Last Posted Date
2012-11-02
Lead Sponsor
University of Rochester
Target Recruit Count
195
Registration Number
NCT00076492
Locations
🇺🇸

University of Rochester Medical Center, Rochester, New York, United States

An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy

Phase 2
Completed
Conditions
First Posted Date
2002-04-09
Last Posted Date
2010-11-16
Lead Sponsor
Cooperative International Neuromuscular Research Group
Target Recruit Count
15
Registration Number
NCT00033189
Locations
🇺🇸

Washington University-St. Louis, St. Louis, Missouri, United States

🇺🇸

Children's National Medical Center, Washington, District of Columbia, United States

Parkinson's Disease Treatment With Coenzyme Q10

Phase 2
Completed
Conditions
First Posted Date
2000-02-28
Last Posted Date
2005-06-24
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Registration Number
NCT00004731
Locations
🇺🇸

University of Rochester, Rochester, New York, United States

© Copyright 2024. All Rights Reserved by MedPath