Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is the coenzyme destined for mitochondrial enzyme complexes involved in oxidative phosphorylation in the production of ATP. It is fundamental for cells that have a high metabolic demand. Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease. FDA does not approve this dietary supplements before sold nor regulate the manufacturing process.
The diet supplements containing ubidecarenone are indicated, as stated in the product label, to assist individuals with cardiovascular complaints including congestive heart failure and systolic hypertension. In the product, ubidecarenone is used to increase the cardiac input as well as for the prevention of several other diseases like Parkinson, fibromyalgia, migraine, periodontal disease and diabetes, based on preclinical studies. It is important to highlight that these products are not FDA approved and it is recommended to use under discretion.
Ain-Shams University Hospital, Cairo, Egypt
Guangyou Duan, Chongqing, Chongqing, China
Dr. Kariadi Central General Hospital, Semarang, Central Java, Indonesia
George Washington University Hospital, Washington, District of Columbia, United States
Trio Fertility, Toronto, Ontario, Canada
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing, Beijing, China
Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China
Fayoum University, Fayoum, Egypt
AdventHealth Translational Research Institute, Orlando, Florida, United States
Department of Infectious Diseases, Aarhus, Aarhus N, Denmark
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