Vitamin E

Generic Name: Vitamin E

Brand Names: Mvc-fluoride, Vitafol-one

Drug Type: Small Molecule

Chemical Formula: C_₂₉H_₅₀O_₂

CAS Number: 59-02-9

Unique Ingredient Identifier: N9PR3490H9

Background: In 1922, vitamin E was demonstrated to be an essential nutrient. Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active. Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage. The antioxidant effects are currently being researched for use in th...

Indication: Vitamin E supplementation is indicated for treatment of vitamin E deficiency which can occur in cystic fibrosis, cholestasis and severe liver disease, abetalipoproteinemia or simply poor diet.

Associated Conditions: Vitamin Deficiency

Associated Therapies: Long-chain omega-3 fatty acid supplementation, Dietary supplementation

Clinical Trials

Role of Vitamin E in Gaucher Disease Patients

Phase 3

Completed

Conditions: Gaucher Disease

Interventions: Drug: Vitamin E

First Posted Date: 2024-01-18

Last Posted Date: 2024-01-18

Lead Sponsor: Ain Shams University

Target Recruit Count: 40

Registration Number: NCT06211478

Locations: 🇪🇬
Ain Shams University, Cairo, Abbasia, Egypt

Using Acetylcysteine and Vitamin E With Psoriasis Vulgaris

Phase 3

Recruiting

Conditions: Psoriasis Vulgaris

Interventions: Drug: Acetyl cysteine
Drug: Vitamin E

First Posted Date: 2023-06-18

Last Posted Date: 2023-06-18

Lead Sponsor: Badr University

Target Recruit Count: 60

Registration Number: NCT05906498

Locations: 🇪🇬
Al-Haud Al-Marsoud Hospital, Cairo, Egypt

Vitamin E Combined With Fruquintinib and Tislelizumab in Microsatellite Stabilized Metastatic Colorectal Cancer Patients

Phase 2

Not yet recruiting

Conditions: Colorectal Cancer
Microsatellite Stable Colorectal Carcinoma

Interventions: Drug: Vitamin E
Drug: Fruquintinib
Drug: Tislelizumab

First Posted Date: 2023-03-16

Last Posted Date: 2023-03-16

Lead Sponsor: Fudan University

Target Recruit Count: 25

Registration Number: NCT05771181

Locations: 🇨🇳
270 Dongan Road, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China

Ketotifen in Non-Alcoholic Fatty Liver Disease Patients

Phase 4

Not yet recruiting

Conditions: Hepatic Disease

Interventions: Drug: Vitamin E
Drug: Ketotifen

First Posted Date: 2022-11-15

Last Posted Date: 2022-11-15

Lead Sponsor: Tanta University

Target Recruit Count: 60

Registration Number: NCT05616442

Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block.

Phase 4

Completed

Conditions: Symptomatic Irreversible Pulpitis

Interventions: Drug: Diclofenac Sodium
Drug: Piroxicam
Drug: Vitamin E
Drug: Tramadol

First Posted Date: 2022-08-05

Last Posted Date: 2022-08-05

Lead Sponsor: Farjad Zafar

Target Recruit Count: 120

Registration Number: NCT05488925

Locations: 🇵🇰
Department of Operative Dentistry, Baqai Dental College, Baqai Medical University., Karachi, Sindh, Pakistan

Clinical Efficacy Analysis of Resveratrol in the Treatment of Primary Ovarian Insufficiency

Not Applicable

Conditions: Primary Ovarian Insufficiency

Interventions: Drug: Vitamin E
Drug: Resveratrol

First Posted Date: 2022-06-08

Last Posted Date: 2022-06-08

Lead Sponsor: Affiliated Hospital of Nantong University

Target Recruit Count: 150

Registration Number: NCT05410093

Locations: 🇨🇳
B ultrasound, Nantong, Jiangsu, China

Vitamin E Efficacy in HI/HA

Phase 2

Withdrawn

Conditions: Hyperinsulinism-Hyperammonemia Syndrome

Interventions: Drug: Vitamin E

First Posted Date: 2021-08-02

Last Posted Date: 2022-12-13

Lead Sponsor: Children's Hospital of Philadelphia

Registration Number: NCT04984798

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Comparing the Effects of Vitamin E, Ursodeoxycholic Acid and Pentoxyfylline on Egyptian Non-alcoholic Steatohepatitis (NASH) Patients

Phase 4

Completed

Conditions: Nonalcoholic Steatohepatitis (NASH)

Interventions: Drug: Vitamin E
Drug: Ursodeoxycholic acid
Drug: Pentoxifylline

First Posted Date: 2021-07-27

Last Posted Date: 2021-07-27

Lead Sponsor: Kafrelsheikh University

Target Recruit Count: 102

Registration Number: NCT04977661

Locations: 🇪🇬
Hepatology, gastroenterology and infectious diseases department at Kafrelsheikh University Hospital, Cairo, Egypt

Vitamin E Dosing Study

Phase 2

Active, not recruiting

Conditions: Nonalcoholic Fatty Liver Disease
Nonalcoholic Steatohepatitis

Interventions: Drug: Placebo
Drug: Vitamin E

First Posted Date: 2021-03-17

Last Posted Date: 2024-10-26

Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Target Recruit Count: 200

Registration Number: NCT04801849

Locations: 🇺🇸
University of California, San Diego, La Jolla, California, United States
🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸
University of California, San Francisco, San Francisco, California, United States

and more 6 locations

Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19

Not Applicable

Completed

Conditions: Pneumonia, Viral
Covid19
ARDS
Oxidative Stress

Interventions: Drug: Vitamin C
Drug: Vitamin E
Drug: Melatonin
Drug: N-acetyl cysteine
Drug: Pentoxifylline

First Posted Date: 2020-09-30

Last Posted Date: 2021-05-21

Lead Sponsor: Unidad Temporal COVID-19 en Centro Citibanamex

Target Recruit Count: 110

Registration Number: NCT04570254

Locations: 🇲🇽
Unidad Temporal COVID-19 en Centro Citibanamex, Mexico City, Mexico

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