Ritonavir
- Generic Name
- Ritonavir
- Brand Names
- Kaletra, Norvir, Paxlovid, Viekira Pak, Ritonavir Mylan
- Drug Type
- Small Molecule
- Chemical Formula
- C37H48N6O5S2
- CAS Number
- 155213-67-5
- Unique Ingredient Identifier
- O3J8G9O825
- Background
Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a booster of other protease inhibi...
- Indication
Ritonavir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
...
- Associated Conditions
- Chronic hepatitis C genotype 1a, Chronic hepatitis C genotype 1b, Human Immunodeficiency Virus Type 1 (HIV-1) Infection, Mild, moderate Novel Coronavirus Infectious Disease (COVID-19)
- Associated Therapies
- -
Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment With Protease Inhibitors
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 30
- Registration Number
- NCT00002361
- Locations
- 🇺🇸
Northwestern Univ / Div of Infect Diseases, Chicago, Illinois, United States
🇺🇸Chase Braxton Health Service, Baltimore, Maryland, United States
🇺🇸Univ of Miami School of Medicine, Miami, Florida, United States
Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- PPD
- Target Recruit Count
- 200
- Registration Number
- NCT00006397
- Locations
- 🇺🇸
East Bay AIDS Ctr, Berkeley, California, United States
🇺🇸JSI Research and Training Institute, Boston, Massachusetts, United States
🇺🇸Univ of Texas Southwestern Med Ctr, Dallas, Texas, United States
Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Glaxo Wellcome
- Target Recruit Count
- 624
- Registration Number
- NCT00009061
- Locations
- 🇺🇸
North Jersey Community Research Initiative, Newark, New Jersey, United States
🇺🇸Nicholas Bellos, Dallas, Texas, United States
🇺🇸Therafirst Med Ctr, Fort Lauderdale, Florida, United States
A Study to Compare Two Anti-HIV Drug Combinations
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 146
- Registration Number
- NCT00002447
- Locations
- 🇺🇸
UCSF - San Francisco Gen Hosp, San Francisco, California, United States
🇺🇸Saint Michael's Med Ctr / Dept of Infectious Diseases, Newark, New Jersey, United States
🇺🇸Associates in Research, Fort Myers, Florida, United States
Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 8
- Registration Number
- NCT00002451
- Locations
- 🇺🇸
Albany Med College, Albany, New York, United States
🇺🇸Univ of Miami School of Medicine, Miami, Florida, United States
🇺🇸SUNY at Stony Brook / Division of Infectious Diseases, Stony Brook, New York, United States
A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 825
- Registration Number
- NCT00002378
- Locations
- 🇺🇸
Northwestern Univ Med Ctr, Chicago, Illinois, United States
🇺🇸Lehigh Valley Hosp, Allentown, Pennsylvania, United States
🇺🇸North Texas Infectious Disease Consultants, Dallas, Texas, United States
A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2012-06-07
- Target Recruit Count
- 900
- Registration Number
- NCT00000919
- Locations
- 🇺🇸
Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States
🇺🇸Marin County Specialty Clinic, San Rafael, California, United States
🇺🇸Emory Hemo Comp Evaluation Clinic / East TN Comp Hemo Ctr, Atlanta, Georgia, United States
The Safety and Effectiveness of Ritonavir in the Treatment of HIV-Related Kaposi's Sarcoma
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2009-02-20
- Lead Sponsor
- Abbott
- Registration Number
- NCT00002366
- Locations
- 🇦🇺
Saint Vincent's Hosp Med Centre, Sydney, Australia
🇦🇺Prince Henry's Hosp / Med Oncology, Sydney, Australia
A Study of Ritonavir (ABT-538) When Used With Nelfinavir in HIV-Infected Patients
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2009-02-20
- Lead Sponsor
- Abbott
- Registration Number
- NCT00002201
- Locations
- 🇺🇸
Johns Hopkins Hosp, Baltimore, Maryland, United States
A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected Adults
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-11-15
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 68
- Registration Number
- NCT00002239
- Locations
- 🇺🇸
UCLA Care Ctr, Los Angeles, California, United States
🇺🇸AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States
🇺🇸Pennsylvania Oncology and Hematology Associates, Philadelphia, Pennsylvania, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.