Thiamine
- Generic Name
- Thiamine
- Brand Names
- Alertonic, Concept Ob, Fortaplex, Infuvite, Infuvite Pediatric, Irospan 24/6 Kit, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Pregvit, Tandem Plus, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C12H17N4OS
- CAS Number
- 70-16-6
- Unique Ingredient Identifier
- 4ABT0J945J
- Background
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose meta...
- Indication
For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
- Associated Conditions
- Anemia, B12 Deficiency Anemia, Beriberi, Cardiovascular Heart Disease caused by Thiamine Deficiency, Folic Acid Deficiency Anemia, Infantile Beriberi, Infection, Iron Deficiency (ID), Neuritis caused by Pregnancy, Secondary anemia, Thiamine Deficiency, Vitamin Deficiency, Wernicke's encephalopathy, Liver disorders
- Associated Therapies
- Nutritional supplementation, Vitamin supplementation, Dietary supplementation
Thiamine and Acute Decompensated Heart Failure: Pilot Study
- First Posted Date
- 2008-05-20
- Last Posted Date
- 2013-08-21
- Lead Sponsor
- Baystate Medical Center
- Target Recruit Count
- 131
- Registration Number
- NCT00680706
- Locations
- 🇺🇸
Baystate Medical Center, Springfield, Massachusetts, United States
🇺🇸Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Oral Thiamine for the Treatment of Painful Diabetic Peripheral Neuropathy
- Conditions
- First Posted Date
- 2006-01-19
- Last Posted Date
- 2015-05-13
- Lead Sponsor
- Loma Linda University
- Registration Number
- NCT00279266
- Locations
- 🇺🇸
Loma Linda University Department of Neurology, Loma Linda, California, United States
A Study to See if Certain Antioxidants and Vitamins Will Keep Lactate Levels Down in Patients Taking Anti-HIV Drugs
- Conditions
- Locations
- 🇺🇸
Univ of Colorado Health Sciences Ctr, Denver, Colorado, United States
🇺🇸Case Western Reserve Univ, Cleveland, Ohio, United States
🇺🇸Univ of Pennsylvania, Philadelphia, Philadelphia, Pennsylvania, United States
Vitamin B Therapy for Hyperlactatemia
- Conditions
- First Posted Date
- 2002-02-22
- Last Posted Date
- 2011-02-28
- Target Recruit Count
- 225
- Registration Number
- NCT00031057
- Locations
- 🇺🇸
Case Western Reserve Univ, Cleveland, Ohio, United States
🇺🇸Univ of North Carolina, Chapel Hill, North Carolina, United States
🇺🇸Beth Israel Med Ctr, New York, New York, United States
Drug Development Updates
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