Thiamine
- Generic Name
- Thiamine
- Brand Names
- Alertonic, Concept Ob, Fortaplex, Infuvite, Infuvite Pediatric, Irospan 24/6 Kit, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Pregvit, Tandem Plus, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C12H17N4OS
- CAS Number
- 70-16-6
- Unique Ingredient Identifier
- 4ABT0J945J
- Background
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose meta...
- Indication
For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
- Associated Conditions
- Anemia, B12 Deficiency Anemia, Beriberi, Cardiovascular Heart Disease caused by Thiamine Deficiency, Folic Acid Deficiency Anemia, Infantile Beriberi, Infection, Iron Deficiency (ID), Neuritis caused by Pregnancy, Secondary anemia, Thiamine Deficiency, Vitamin Deficiency, Wernicke's encephalopathy, Liver disorders
- Associated Therapies
- Nutritional supplementation, Vitamin supplementation, Dietary supplementation
Vitamin C & Thiamine to Treat Sepsis and Septic Shock
- First Posted Date
- 2018-07-19
- Last Posted Date
- 2022-09-28
- Lead Sponsor
- Trinity Health Of New England
- Target Recruit Count
- 120
- Registration Number
- NCT03592277
- Locations
- 🇺🇸
Saint Francis Hospital and Medical Center, Hartford, Connecticut, United States
Thiamine as a Renal Protective Agent in Septic Shock
- Conditions
- Interventions
- First Posted Date
- 2018-06-08
- Last Posted Date
- 2023-06-27
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Target Recruit Count
- 95
- Registration Number
- NCT03550794
- Locations
- 🇺🇸
Northshore University Hospital, Manhasset, New York, United States
🇺🇸Long Island Jewish Hospital, Queens, New York, United States
🇺🇸Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Vitamin C, Thiamine, and Steroids in Sepsis
- Conditions
- Interventions
- First Posted Date
- 2018-04-26
- Last Posted Date
- 2021-04-13
- Lead Sponsor
- Emory University
- Target Recruit Count
- 501
- Registration Number
- NCT03509350
- Locations
- 🇺🇸
University of Arizona, Tucson, Arizona, United States
🇺🇸Yale New Haven Hospital, New Haven, Connecticut, United States
🇺🇸Christiana Care, Newark, Delaware, United States
Vitamin C in Post-cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2018-04-26
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Amsterdam UMC, location VUmc
- Target Recruit Count
- 270
- Registration Number
- NCT03509662
- Locations
- 🇳🇱
VU Medical Center, Amsterdam, Noord-Holland, Netherlands
Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets
- Conditions
- Interventions
- First Posted Date
- 2018-02-14
- Last Posted Date
- 2020-08-11
- Lead Sponsor
- Texas Tech University Health Sciences Center
- Target Recruit Count
- 120
- Registration Number
- NCT03432572
- Locations
- 🇺🇸
Texas Tech University Health Sciences Center, Lubbock, Texas, United States
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
- Conditions
- Interventions
- First Posted Date
- 2018-02-05
- Last Posted Date
- 2021-09-21
- Lead Sponsor
- Community Medical Center, Toms River, NJ
- Target Recruit Count
- 140
- Registration Number
- NCT03422159
- Locations
- 🇺🇸
Community Medical Center, Toms River, New Jersey, United States
🇺🇸Monmouth Medical Center, Southern Campus, Lakewood, New Jersey, United States
The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock
- Conditions
- Interventions
- First Posted Date
- 2017-11-07
- Last Posted Date
- 2019-02-19
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 5
- Registration Number
- NCT03335124
- Locations
- 🇸🇮
Department of Gastroenterology, UMC Ljubljana, Ljubljana, Slovenia
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial
- Conditions
- Interventions
- First Posted Date
- 2017-11-06
- Last Posted Date
- 2019-10-10
- Target Recruit Count
- 216
- Registration Number
- NCT03333278
- Locations
- 🇦🇺
Alfred Hospital, Melbourne, Victoria, Australia
🇦🇺Royal Melbourne Hospital, Melbourne, Victoria, Australia
🇦🇺Austin Health, Heidelberg, Victoria, Australia
High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation
- Conditions
- Interventions
- First Posted Date
- 2017-08-28
- Last Posted Date
- 2021-10-19
- Lead Sponsor
- UNC Lineberger Comprehensive Cancer Center
- Target Recruit Count
- 66
- Registration Number
- NCT03263442
- Locations
- 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
Thiamine Supplementation in Patients With Septic Shock
- Conditions
- Interventions
- First Posted Date
- 2017-04-21
- Last Posted Date
- 2019-03-15
- Lead Sponsor
- The Cleveland Clinic
- Registration Number
- NCT03122678
- Locations
- 🇺🇸
Cleveland Clinic Florida, Weston, Florida, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.