MedPath

Cefuroxime

Generic Name
Cefuroxime
Brand Names
Ceftin
Drug Type
Small Molecule
Chemical Formula
C16H16N4O8S
CAS Number
55268-75-2
Unique Ingredient Identifier
O1R9FJ93ED
Background

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.

Indication

For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.

Associated Conditions
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Animal bite, Bacterial Infections, Bone and Joint Infections, Impetigo, Lower Respiratory Tract Infection (LRTI), Lyme Disease, Maxillary Sinusitis, Meningitis, Neisseria Gonorrhoeae Infection, Septicemia, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Bacterial otitis media, Mild Streptococcal pharyngitis, Mild Streptococcal tonsillitis, Moderate Streptococcal pharyngitis, Moderate Streptococcal tonsillitis

The Preventive Infection Role of One Week Antibiotics Before Minimally Invasive Upper Tract Lithotomy

Early Phase 1
Conditions
Complication of Surgical Procedure
Interventions
First Posted Date
2016-06-03
Last Posted Date
2019-10-01
Lead Sponsor
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Target Recruit Count
150
Registration Number
NCT02789579
Locations
🇨🇳

Department of Pharmacy, Xinhua Hospital, Shanghai Jiaotong University School of Medicine.Kongjiang Road 1665,, Shanghai, Shanghai, China

Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis

Phase 4
Completed
Conditions
Surgical Wound Infection
Interventions
First Posted Date
2015-07-22
Last Posted Date
2020-01-14
Lead Sponsor
Hospital Universitari Vall d'Hebron Research Institute
Target Recruit Count
536
Registration Number
NCT02505581
Locations
🇪🇸

Hospital Universitari de Girona Dr. Josep Trueta, Girona, Spain

🇪🇸

Hospital de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain

🇪🇸

Hospital General Universitario Vall d´Hebron, Barcelona, Spain

Continuous Antibiotic Prophylaxis in Colorectal Surgery

Phase 2
Completed
Conditions
Surgical Site Infection
Interventions
First Posted Date
2015-05-15
Last Posted Date
2019-10-10
Lead Sponsor
University of Leeds
Target Recruit Count
90
Registration Number
NCT02445859
Locations
🇬🇧

Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom

Antibiotics and Gut Microbiota Among Newborn Infants

Phase 4
Completed
Conditions
Surgical Wound Infection
Infection; Cesarean Section
Complications; Cesarean Section
Interventions
First Posted Date
2014-02-27
Last Posted Date
2014-08-12
Lead Sponsor
Odense University Hospital
Target Recruit Count
42
Registration Number
NCT02072798
Locations
🇩🇰

Odense University Hospital, Odense, Fyn, Denmark

RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean Section

Phase 4
Withdrawn
Conditions
Postoperative Infection
Interventions
First Posted Date
2013-12-11
Last Posted Date
2015-04-21
Lead Sponsor
Odense University Hospital
Registration Number
NCT02009098
Locations
🇩🇰

Hospital of South West Jutland, Esbjerg, Denmark

🇩🇰

Odense University Hospital, Odense, Denmark

🇩🇰

Hvidovre Hospital, Hvidovre, Denmark

Antibiotic Prophylaxis for Transrectal Prostate Biopsy

Phase 4
Completed
Conditions
Infection
Interventions
First Posted Date
2012-08-08
Last Posted Date
2019-06-25
Lead Sponsor
Northwestern University
Target Recruit Count
563
Registration Number
NCT01659866
Locations
🇺🇸

Northwestern University Department of Urology, Chicago, Illinois, United States

Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome

Phase 4
Completed
Conditions
Erythema Migrans
Post-Lyme Disease Symptoms
Interventions
First Posted Date
2012-01-25
Last Posted Date
2012-01-25
Lead Sponsor
University Medical Centre Ljubljana
Target Recruit Count
544
Registration Number
NCT01518192
Locations
🇸🇮

Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia

🇸🇮

Department of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia, Ljubljana, Slovenia

Tailored Antibiotics Prophylaxis for Percutaneous Endoscopic Gastrostomy

Not Applicable
Conditions
The Patients Who Receive Percutaneous Endoscopic Gastrostomy
Peristomal Wound Infection After the Operation of PEG
Prophylactic Antibiotics Before PEG
Interventions
Drug: Tailored antibiotic
First Posted Date
2010-11-10
Last Posted Date
2010-11-10
Lead Sponsor
National Cheng Kung University
Target Recruit Count
100
Registration Number
NCT01237730
Locations
🇨🇳

National Cheng Kung University Hospital, Tainan, Taiwan

Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section

Phase 4
Completed
Conditions
Surgical Site Infections
Interventions
First Posted Date
2010-06-07
Last Posted Date
2010-06-07
Lead Sponsor
Attikon Hospital
Target Recruit Count
176
Registration Number
NCT01138852

Daptomycin as Antibiotic Prophylaxis of Sternal Wound Infections

Phase 4
Completed
Conditions
Wound Infection
Interventions
First Posted Date
2010-03-05
Last Posted Date
2012-04-17
Lead Sponsor
Hannover Medical School
Target Recruit Count
650
Registration Number
NCT01080963
Locations
🇩🇪

Hannover Medical School, Department of Cardiothoracic, Transplant and Vascular surgery, Hannover, Germany

© Copyright 2025. All Rights Reserved by MedPath