Midazolam

Generic Name
Midazolam
Brand Names
Buccolam, Busulfex, Nayzilam, Seizalam
Drug Type
Small Molecule
Chemical Formula
C18H13ClFN3
CAS Number
59467-70-8
Unique Ingredient Identifier
R60L0SM5BC
Background

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...

Indication

Midazolam has different indications depending on its formulation by the FDA.

Nasal
...

Associated Conditions
Epileptic seizure, Status Epilepticus
Associated Therapies
Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy

Evaluation of the Analgesic Effect of Midazolam and Ketamine as an Additive to Intrathecal Bupivacaine in Patients Undergoing Cesarean Section

First Posted Date
2011-07-28
Last Posted Date
2012-05-17
Lead Sponsor
Qazvin University Of Medical Sciences
Target Recruit Count
90
Registration Number
NCT01404442
Locations
🇮🇷

Qazvin university of medical science, Qazvin, Iran, Islamic Republic of

Evaluation of Pediatric Procedural Sedation With Rectal Chloral Hydrate or Intranasal Midazolam

First Posted Date
2011-07-26
Last Posted Date
2013-06-20
Lead Sponsor
University of Sao Paulo
Registration Number
NCT01402596
Locations
🇧🇷

University of Sao Paulo, Sao Paulo, SP, Brazil

A Study to Assess the Effect Tasimelteon on the Cytochrome P450 3A4 and 2C8 Enzymes in Healthy Subjects

First Posted Date
2011-07-26
Last Posted Date
2014-02-17
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT01402076
Locations
🇺🇸

Bio-Kinetic Clinical Applications, Springfield, Missouri, United States

Cytochrom p450 3A4 and 1A2 Phenotyping for the Individualization of Treatment With Sunitinib or Erlotinib in Cancer Patients

First Posted Date
2011-07-26
Last Posted Date
2016-02-02
Lead Sponsor
Markus Joerger
Target Recruit Count
54
Registration Number
NCT01402089
Locations
🇨🇭

Cantonal Hospital St.Gallen, St.Gallen, Switzerland

A Study of LY2228820 in Participants With Advanced Cancer

First Posted Date
2011-07-14
Last Posted Date
2020-03-24
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
89
Registration Number
NCT01393990
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., San Antonio, Texas, United States

Nasogastric Tube Insertion Using Midazolam in the Emergency Department

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-06-17
Last Posted Date
2013-07-22
Lead Sponsor
University of Vermont
Target Recruit Count
49
Registration Number
NCT01375634
Locations
🇺🇸

Fletcher Allen Health Care Emergency Department, Burlington, Vermont, United States

Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2011-06-10
Last Posted Date
2018-01-18
Lead Sponsor
Wayne Goodman MD
Target Recruit Count
3
Registration Number
NCT01371110
Locations
🇺🇸

Clinical Research Centers at Icahn School of Medicine at Mount Sinai, New York, New York, United States

Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics

First Posted Date
2011-05-19
Last Posted Date
2011-05-19
Lead Sponsor
Govind Ballabh Pant Hospital
Target Recruit Count
120
Registration Number
NCT01356121
Locations
🇮🇳

Prof Barjesh Chander Sharma, New Delhi, Delhi, India

Cycling of Sedative Infusions in Critically Ill Pediatric Patients

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2011-04-11
Last Posted Date
2019-01-15
Lead Sponsor
Javier Gelvez, MD
Target Recruit Count
25
Registration Number
NCT01333059
Locations
🇺🇸

Cook Children's Medical Center, Fort Worth, Texas, United States

Ultrasound-guided Axillary Plexus Block - Dose Reduction of Prilocaine

First Posted Date
2011-03-07
Last Posted Date
2011-07-12
Lead Sponsor
Helios Research Center
Target Recruit Count
120
Registration Number
NCT01309360
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