Midazolam
- Generic Name
- Midazolam
- Brand Names
- Buccolam, Busulfex, Nayzilam, Seizalam
- Drug Type
- Small Molecule
- Chemical Formula
- C18H13ClFN3
- CAS Number
- 59467-70-8
- Unique Ingredient Identifier
- R60L0SM5BC
- Background
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...
- Indication
Midazolam has different indications depending on its formulation by the FDA.
Nasal
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- Associated Conditions
- Epileptic seizure, Status Epilepticus
- Associated Therapies
- Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy
Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects
- Conditions
- Interventions
- First Posted Date
- 2008-02-14
- Last Posted Date
- 2017-09-11
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 23
- Registration Number
- NCT00615212
- Locations
- 🇺🇸
GSK Investigational Site, Buffalo, New York, United States
Clowns as Treatment for Preoperative Anxiety in Children: A Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2008-02-07
- Last Posted Date
- 2008-02-07
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 65
- Registration Number
- NCT00609960
- Locations
- 🇮🇱
Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
Sedation and Analgesia for Transjugular Liver Biopsy: A Randomized Double Blind Placebo Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2008-01-17
- Last Posted Date
- 2008-01-17
- Lead Sponsor
- Erasme University Hospital
- Target Recruit Count
- 180
- Registration Number
- NCT00596414
- Locations
- 🇧🇪
Hopital Erasme - Dpt of Gastroenterology, Brussels, Belgium
Psychological Influences on Postoperative Recovery
- Conditions
- Interventions
- First Posted Date
- 2007-12-27
- Last Posted Date
- 2023-09-07
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 241
- Registration Number
- NCT00581139
- Locations
- 🇺🇸
Yale University Department of Anesthesiology, New Haven, Connecticut, United States
Safety of Driving After Minor Surgery with Monitored Anesthesia Care
- Conditions
- Interventions
- First Posted Date
- 2007-12-20
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 625
- Registration Number
- NCT00577200
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
Premedication With Oral Midazolam in Patients Undergoing Rigid Cystoscopy: A Randomized, Double-blind, Placebo-controlled Trial
- Conditions
- First Posted Date
- 2007-11-26
- Last Posted Date
- 2010-07-07
- Lead Sponsor
- Hospital Authority, Hong Kong
- Target Recruit Count
- 120
- Registration Number
- NCT00563069
- Locations
- 🇨🇳
Department of Surgery, Prince of Wales Hospital, Hong Kong, China
Evaluate the Use of Paravertebral Block in Reconstructive Breast Surgery
- Conditions
- Interventions
- First Posted Date
- 2007-10-11
- Last Posted Date
- 2015-04-13
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 89
- Registration Number
- NCT00542542
- Locations
- 🇺🇸
UT MD Anderson Cancer Center, Houston, Texas, United States
Phase I Trail for Intramuscular Administration of Midazolam Using An Autoinjector
- First Posted Date
- 2007-09-24
- Last Posted Date
- 2007-09-24
- Lead Sponsor
- U.S. Army Office of the Surgeon General
- Target Recruit Count
- 39
- Registration Number
- NCT00534378
- Locations
- 🇺🇸
BASi Baltimore Clinical Research Unit, Baltimore, Maryland, United States
28-day Repeat Dose and Drug Interaction Study With Orvepitant (GW823296)
- Conditions
- Interventions
- First Posted Date
- 2007-08-06
- Last Posted Date
- 2017-08-04
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 36
- Registration Number
- NCT00511654
- Locations
- 🇩🇪
GSK Investigational Site, Berlin, Germany
Dexmedetomidine Versus Midazolam for Continuous Sedation in the Intensive Care Unit (ICU)
- Conditions
- Interventions
- First Posted Date
- 2007-06-01
- Last Posted Date
- 2012-05-07
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 501
- Registration Number
- NCT00481312
- Locations
- 🇧🇪
ULB Erasme, Route de Lennik, Brussels, Belgium
🇧🇪UZ Brussel, Intensive Care Dept. Laarbeeklaan 101, Brussels, Belgium
🇧🇪Universitaer Ziekenhuis Gent, Intensieve Zorgen, De Pintelaan 185, Gent, Belgium
Drug Development Updates
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