Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Comparison of Propofol-fentanyl and Midazolam-fentanyl for Conscious Sedation
- First Posted Date
- 2012-12-13
- Last Posted Date
- 2012-12-13
- Lead Sponsor
- Tehran University of Medical Sciences
- Target Recruit Count
- 60
- Registration Number
- NCT01749579
- Locations
- 🇮🇷
Imam Khomeini Hospital, Tehran, Iran, Islamic Republic of
Remifentanil Versus Propofol for TCI Sedation of Patients Undergoing Gastrointestinal Endoscopic Procedures
- First Posted Date
- 2012-12-11
- Last Posted Date
- 2012-12-11
- Lead Sponsor
- Fundación Universitaria de Ciencias de la Salud
- Target Recruit Count
- 69
- Registration Number
- NCT01746641
- Locations
- 🇨🇴
Fundación Universitaria de Ciencias de la Salud, Bogota, Colombia
The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure
- Conditions
- Interventions
- First Posted Date
- 2012-12-04
- Last Posted Date
- 2021-06-07
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 438
- Registration Number
- NCT01739933
- Locations
- 🇺🇸
Baystate Medical Center, Springfield, Massachusetts, United States
🇺🇸Mission Hospital, Asheville, North Carolina, United States
🇺🇸Baton Rouge General Medical Center and Our Lady of The Lakes Regional Medical Center, Baton Rouge, Louisiana, United States
Analysis of Cisatracurium Consumption in Balanced Anesthesia With 1% Sevoflurane, and With Only Sevoflurane, Using a Closed-loop Computer Controlled System Infusion.
- Conditions
- Interventions
- First Posted Date
- 2012-11-29
- Last Posted Date
- 2012-11-29
- Lead Sponsor
- Tianjin Medical University General Hospital
- Target Recruit Count
- 156
- Registration Number
- NCT01736371
- Locations
- 🇨🇳
Tianjin Medical University, Tianjin, China
Developing Anesthesia as Post Traumatic Stress Disorder (PTSD) Therapy
- Conditions
- Interventions
- First Posted Date
- 2012-11-29
- Last Posted Date
- 2016-10-13
- Target Recruit Count
- 293
- Registration Number
- NCT01736020
- Locations
- 🇺🇸
University of California, Irvine, Irvine, California, United States
Etomidate Emulsion for Sedation in Patients Scheduled for Upper Gastrointestinal (GI) Endoscopy
- Conditions
- Interventions
- First Posted Date
- 2012-11-20
- Last Posted Date
- 2013-05-13
- Lead Sponsor
- Jiangsu Nhwa Pharmaceutical Co., Ltd.
- Target Recruit Count
- 328
- Registration Number
- NCT01729897
Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.
- Conditions
- Interventions
- First Posted Date
- 2012-10-18
- Last Posted Date
- 2013-10-22
- Lead Sponsor
- Prince of Songkla University
- Target Recruit Count
- 140
- Registration Number
- NCT01709422
- Locations
- 🇹🇭
NKC Institues of Gastroenterology and Hepatology, Prince of Songkla University, Hatyai, Songkhla, Thailand
Effect of Depth of Total Intravenous Anesthesia Using Propofol on Postoperative Cognitive Dysfunction
- First Posted Date
- 2012-10-17
- Last Posted Date
- 2013-05-31
- Lead Sponsor
- Xiangya Hospital of Central South University
- Target Recruit Count
- 300
- Registration Number
- NCT01708837
- Locations
- 🇨🇳
XiangYa Hospital, Central South University, Changsha, Hunan, China
Analgesic Effect of IV Acetaminophen in Tonsillectomies
- First Posted Date
- 2012-09-25
- Last Posted Date
- 2017-04-06
- Lead Sponsor
- Nationwide Children's Hospital
- Target Recruit Count
- 250
- Registration Number
- NCT01691690
- Locations
- 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States
Vasopressin to Prevent Hypotension During Beach Chair Surgery
- Conditions
- Interventions
- First Posted Date
- 2012-09-19
- Last Posted Date
- 2017-02-27
- Lead Sponsor
- Chonnam National University Hospital
- Target Recruit Count
- 74
- Registration Number
- NCT01687894
- Locations
- 🇰🇷
Department of Anesthesiology and Pain Medicine, Gwangju, Korea, Republic of
Drug Development Updates
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