MedPath

Nicotinamide

Generic Name
Nicotinamide
Brand Names
Alertonic, Fortaplex, Infuvite, Infuvite Pediatric, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Nicomide, Pregvit, Tandem Plus
Drug Type
Small Molecule
Chemical Formula
C6H6N2O
CAS Number
98-92-0
Unique Ingredient Identifier
25X51I8RD4
Background

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

Indication

用于防治糙皮病等烟酸缺乏病，也用于防治心脏传导阻滞。

Associated Conditions
Gastrointestinal insufficiency, Hepatic Insufficiency, Macrocytic anemia, Secondary anemia, Vitamin Deficiency, Severe debilitation
Associated Therapies
Dietary and Nutritional Therapies, Nutritional supplementation, Dietary supplementation
Clinical Trials
Related News

Does High-dose Vitamin B3 Supplementation Prevent Major Adverse Kidney Events During Septic Shock?

Phase 3
Recruiting
Conditions
Acute Kidney Injury
Septic Shock
Nicotinamide
Mortality
Interventions
Drug: placebo treatment
First Posted Date
2020-10-19
Last Posted Date
2022-12-12
Lead Sponsor
Centre Hospitalier Universitaire, Amiens
Target Recruit Count
310
Registration Number
NCT04589546
Locations
🇫🇷

CHU Amiens, Amiens, France

Protection From Acute Kidney Injury (AKI) With Basis™ Treatment

Phase 2
Completed
Conditions
AKI
Interventions
Drug: Placebo
First Posted Date
2020-04-13
Last Posted Date
2024-04-23
Lead Sponsor
Mayo Clinic
Target Recruit Count
54
Registration Number
NCT04342975
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

Early Phase 1
Recruiting
Conditions
Allogeneic Hematopoietic Cell Transplantation
Interventions
First Posted Date
2020-04-02
Last Posted Date
2025-04-16
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
20
Registration Number
NCT04332341
Locations
🇺🇸

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Nicotinamide Riboside as an Enhancer of Exercise Therapy in Hypertensive Older Adults (The NEET Trial)

Phase 1
Completed
Conditions
Hypertension
Interventions
Behavioral: Walking Exercise
First Posted Date
2019-10-02
Last Posted Date
2024-06-06
Lead Sponsor
University of Florida
Target Recruit Count
147
Registration Number
NCT04112043
Locations
🇺🇸

UF Institute on Aging, Gainesville, Florida, United States

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease

Phase 1
Recruiting
Conditions
Sickle Cell Disease
Interventions
First Posted Date
2019-08-14
Last Posted Date
2023-04-05
Lead Sponsor
EpiDestiny, Inc.
Target Recruit Count
20
Registration Number
NCT04055818
Locations
🇺🇸

University of Illinois at Chicago College of Medicine, Chicago, Illinois, United States

Nutritional Support and Prophylaxis Doses of Azithromycin for Pregnant Women - Mumta Pregnant Women Trial

Not Applicable
Active, not recruiting
Conditions
Undernutrition
Interventions
Dietary Supplement: Balanced-energy protein (BEP)
First Posted Date
2019-07-09
Last Posted Date
2022-10-13
Lead Sponsor
Vital Pakistan Trust
Target Recruit Count
1884
Registration Number
NCT04012177
Locations
🇵🇰

Peri-urban slum (Rehri Goth), Karachi, Sindh, Pakistan

Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial

Phase 2
Active, not recruiting
Conditions
Non-melanoma Skin Cancer
Carcinoma, Squamous Cell
Carcinoma, Basal Cell
Interventions
Drug: Placebo oral capsule
First Posted Date
2018-12-07
Last Posted Date
2023-04-06
Lead Sponsor
Women's College Hospital
Target Recruit Count
120
Registration Number
NCT03769285
Locations
🇨🇦

Toronto General Hospital, University Health Network, Toronto, Ontario, Canada

Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia

Phase 2
Withdrawn
Conditions
Friedreich Ataxia
Interventions
Drug: Placebo
First Posted Date
2018-12-03
Last Posted Date
2024-01-24
Lead Sponsor
RWTH Aachen University
Registration Number
NCT03761511
Locations
🇫🇷

Service de génétique médicale - Hôpital La Pitié Salpetrière, Paris, France

🇦🇹

Medical University Innsbruck, Innsbruck, Austria

🇮🇹

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy

and more 4 locations

Study of Nicotinamide in Early Onset Preeclampsia

Phase 2
Completed
Conditions
Pregnancy Related
Pre-Eclampsia
Interventions
First Posted Date
2018-02-01
Last Posted Date
2022-09-08
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
23
Registration Number
NCT03419364
Locations
🇺🇸

UNC at Chapel Hill, Chapel Hill, North Carolina, United States

DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide.

Early Phase 1
Completed
Conditions
Melasma
Interventions
Device: colorimetry measurement
Drug: sunscreen
First Posted Date
2018-01-08
Last Posted Date
2018-01-09
Lead Sponsor
Universidad Autonoma de San Luis Potosí
Target Recruit Count
28
Registration Number
NCT03392623
© Copyright 2025. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy