Nicotinamide
- Generic Name
- Nicotinamide
- Brand Names
- Alertonic, Fortaplex, Infuvite, Infuvite Pediatric, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Nicomide, Pregvit, Tandem Plus
- Drug Type
- Small Molecule
- Chemical Formula
- C6H6N2O
- CAS Number
- 98-92-0
- Unique Ingredient Identifier
- 25X51I8RD4
- Background
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
- Indication
用于防治糙皮病等烟酸缺乏病，也用于防治心脏传导阻滞。
- Associated Conditions
- Gastrointestinal insufficiency, Hepatic Insufficiency, Macrocytic anemia, Secondary anemia, Vitamin Deficiency, Severe debilitation
- Associated Therapies
- Dietary and Nutritional Therapies, Nutritional supplementation, Dietary supplementation
Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus
- Conditions
- Systemic Lupus Erythematosus RashCutaneous Lupus Erythematosus
- Interventions
- First Posted Date
- 2017-08-24
- Last Posted Date
- 2021-02-02
- Lead Sponsor
- Second Xiangya Hospital of Central South University
- Target Recruit Count
- 40
- Registration Number
- NCT03260166
- Locations
- 🇨🇳
The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
Healthy Combine Study
- Conditions
- Healthy
- Interventions
- First Posted Date
- 2017-05-02
- Last Posted Date
- 2024-02-23
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 39
- Registration Number
- NCT03136705
- Locations
- 🇺🇸
Center for Translational Metabolism and Health (CTMH), Northwestern University, Chicago, Illinois, United States
Nicotinamide as an Early Alzheimer's Disease Treatment
- Conditions
- Alzheimer's DiseaseMild Cognitive Impairment
- Interventions
- Drug: Placebo Comparator
- First Posted Date
- 2017-02-23
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 46
- Registration Number
- NCT03061474
- Locations
- 🇺🇸
University of California, Irvine, Irvine, California, United States
🇺🇸University of California, Los Angeles, Los Angeles, California, United States
Anticancer Activity of Nicotinamide on Lung Cancer
- First Posted Date
- 2015-04-15
- Last Posted Date
- 2020-01-27
- Lead Sponsor
- Il Yeong Park, Ph.D.
- Target Recruit Count
- 110
- Registration Number
- NCT02416739
- Locations
- 🇰🇷
Chonnam National University Hwasun Hospital, Hwasun, Chonnam, Korea, Republic of
The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE
- Conditions
- Chronic Kidney Disease
- Interventions
- Drug: Placebo (for Nicotinamide)Drug: Placebo (for lanthanum carbonate)
- First Posted Date
- 2014-10-07
- Last Posted Date
- 2021-08-02
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 205
- Registration Number
- NCT02258074
- Locations
- 🇺🇸
NorthShore University Health System, Chicago, Illinois, United States
🇺🇸Denver Nephrology Research, Denver, Colorado, United States
🇺🇸Northwestern University, Chicago, Illinois, United States
Phase I Study of Nicotinamide for Early Onset Preeclampsia
- Conditions
- Pregnancy Induced HypertensionHypertensionSuperimposed Preeclampsia
- Interventions
- First Posted Date
- 2014-08-11
- Last Posted Date
- 2018-11-02
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 10
- Registration Number
- NCT02213094
- Locations
- 🇺🇸
University of North Carolina Women's Hospital, Chapel Hill, North Carolina, United States
Effect of Nicotinamide in Friedreich's Ataxia
- First Posted Date
- 2012-05-02
- Last Posted Date
- 2017-07-02
- Lead Sponsor
- Imperial College London
- Target Recruit Count
- 40
- Registration Number
- NCT01589809
- Locations
- 🇬🇧
National Hospital for Neurology and Neurosurgery, London, United Kingdom
🇬🇧NIHR/Wellcome Trust Imperial CRF, London, Hammersmith, United Kingdom
Clinical Trial of 4% Niacinamide Versus 0.05% Desonide for the Treatment of Axillar Hyperpigmentation
- Conditions
- Hyperpigmentation
- Interventions
- First Posted Date
- 2012-03-02
- Last Posted Date
- 2012-11-29
- Lead Sponsor
- Universidad Autonoma de San Luis Potosí
- Target Recruit Count
- 28
- Registration Number
- NCT01542138
- Locations
- 🇲🇽
Dermatology Department. Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosi, Mexico
Study to Test the Effectiveness of a New Treatment for Scalp Psoriasis
- Conditions
- Psoriasis
- Interventions
- First Posted Date
- 2011-06-08
- Last Posted Date
- 2011-06-08
- Lead Sponsor
- DermiPsor, Ltd.
- Target Recruit Count
- 160
- Registration Number
- NCT01368887
- Locations
- 🇺🇸
Boston VA Hospital, Boston, Massachusetts, United States
🇺🇸Brockton VA Hospital, Brockton, Massachusetts, United States
Nicotinamide in Hemodialysis Patients With Hyperphosphatemia
- Conditions
- Chronic Kidney DiseaseHemodialysisHyperphosphatemia
- Interventions
- First Posted Date
- 2010-09-14
- Last Posted Date
- 2012-01-18
- Lead Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
- Target Recruit Count
- 252
- Registration Number
- NCT01200784
Drug Development Updates
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