Povidone-iodine
- Generic Name
- Povidone-iodine
- Brand Names
- Betadine, Kenalog, Marbeta, Marcaine, P-Care M, P-Care MG, P-care, P-care X, Summer's Eve Medicated
- Drug Type
- Small Molecule
- CAS Number
- 25655-41-8
- Unique Ingredient Identifier
- 85H0HZU99M
- Background
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less toxic in mice than tincture of iodine. Human clinical trials showed the product to be superior to other iodine formulations. Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic.
- Indication
For topical application in the treatment and prevention of infection in wounds.
- Associated Conditions
- Skin Infections
- Associated Therapies
- Skin disinfection, Antiseptic skin preparation therapy, Irrigation of the ocular surface therapy, Prepping of the periocular region
Topical Antisepsis in Head and Neck Cancer Surgery
- Conditions
- Head and Neck Cancer
- First Posted Date
- 2021-01-22
- Last Posted Date
- 2022-02-07
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 25
- Registration Number
- NCT04721626
- Locations
- 🇺🇸
Froedtert Hospital & the Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Virucidal Effect of Povidone Iodine on COVID-19 In-Vivo
- Conditions
- COVID19
- Interventions
- First Posted Date
- 2020-09-16
- Last Posted Date
- 2022-01-25
- Lead Sponsor
- DR. MALA KHAN
- Target Recruit Count
- 200
- Registration Number
- NCT04549376
- Locations
- 🇧🇩
Dhaka Medical College, Dhaka, Bangladesh
Halodine Nasal Antiseptic in Patients With COVID-19
- Conditions
- SARS-CoV-2 Infection
- Interventions
- First Posted Date
- 2020-08-18
- Last Posted Date
- 2021-02-10
- Lead Sponsor
- Halodine LLC
- Target Recruit Count
- 40
- Registration Number
- NCT04517188
SHIELD Study: Using Naso-oropharyngeal Antiseptic Decolonization to Reduce COVID-19 Viral Shedding
- Conditions
- SARS-CoV 2COVID-19
- Interventions
- First Posted Date
- 2020-07-20
- Last Posted Date
- 2022-07-14
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 245
- Registration Number
- NCT04478019
- Locations
- 🇺🇸
University of Wisconsin-Madison, Madison, Wisconsin, United States
Betadine Effect on Nasal Mucosa Cilia
- First Posted Date
- 2020-07-07
- Last Posted Date
- 2021-02-12
- Lead Sponsor
- Boston Medical Center
- Registration Number
- NCT04457765
- Locations
- 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
Povidone-Iodine Rinses in the Management of COVID-19
- First Posted Date
- 2020-06-29
- Last Posted Date
- 2022-07-11
- Lead Sponsor
- St. Paul's Hospital, Canada
- Target Recruit Count
- 5
- Registration Number
- NCT04449965
- Locations
- 🇨🇦
St. Paul's Hospital, Vancouver, British Columbia, Canada
A Preventive Treatment for Migrant Workers at High-risk of COVID-19
- Conditions
- Covid-19
- Interventions
- Dietary Supplement: Vitamin C
- First Posted Date
- 2020-06-24
- Last Posted Date
- 2020-10-19
- Lead Sponsor
- National University Hospital, Singapore
- Target Recruit Count
- 4257
- Registration Number
- NCT04446104
- Locations
- 🇸🇬
Tuas South Dormitory, Singapore, Singapore
Povidone-Iodine Vs Essential Oil Vs Tap Water Gargling For COVID-19 Patients
- Conditions
- COVID-19
- Interventions
- First Posted Date
- 2020-06-01
- Last Posted Date
- 2020-07-21
- Lead Sponsor
- Universiti Sains Islam Malaysia
- Target Recruit Count
- 20
- Registration Number
- NCT04410159
- Locations
- 🇲🇾
Universiti Kebangsaan Malaysia Medical Centre, Bandar Tun Razak, Wilayah Persekutuan Kuala Lumpur, Malaysia
SINUS WASH Pilot Study in Adults Testing Positive for COVID-19
- First Posted Date
- 2020-05-19
- Last Posted Date
- 2021-09-17
- Lead Sponsor
- Hampshire Hospitals NHS Foundation Trust
- Target Recruit Count
- 40
- Registration Number
- NCT04393792
- Locations
- 🇬🇧
Hampshire Hospitals NHS Foundation Trust, Basingstoke, Hampshire, United Kingdom
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19
- First Posted Date
- 2020-05-01
- Last Posted Date
- 2020-10-26
- Lead Sponsor
- Poitiers University Hospital
- Target Recruit Count
- 24
- Registration Number
- NCT04371965
- Locations
- 🇫🇷
University Hospital of Poitiers, Poitiers, France
Drug Development Updates
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