Dornase alfa
- Generic Name
- Dornase alfa
- Brand Names
- Pulmozyme
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 143831-71-4
- Unique Ingredient Identifier
- 953A26OA1Y
- Background
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphool...
- Indication
Used as adjunct therapy in the treatment of cystic fibrosis.
- Associated Conditions
- Cystic Fibrosis (CF)
- Associated Therapies
- -
Ocrevus Zunovo approved by the FDA
Roche is a research-based healthcare company with two divisions: Pharmaceuticals and Diagnostics. Pharmaceuticals include Roche Pharmaceuticals and Chugai, while Diagnostics comprises Diabetes Care, Molecular Diagnostics, Professional Diagnostics, and Tissue Diagnostics. Roche develops medicines for oncology, immunology, infectious diseases, ophthalmology, and neuroscience, and offers products for researchers in cell analysis, gene expression, genome sequencing, and nucleic acid purification.
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