Verapamil

Generic Name
Verapamil
Brand Names
Calan, Isoptin, Tarka, Verelan
Drug Type
Small Molecule
Chemical Formula
C27H38N2O4
CAS Number
52-53-9
Unique Ingredient Identifier
CJ0O37KU29
Background

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like diltiazem and flunarizine, bu...

Indication

Verapamil is indicated in the treatment of vasopastic (i.e. Prinzmetal's) angina, unstable angina, and chronic stable angina. It is also indicated to treat hypertension, for the prophylaxis of repetitive paroxysmal supraventricular tachycardia, and in combination with digoxin to control ventricular rate in patients with atrial fibrillation or atrial flutter....

Associated Conditions
Chronic Stable Angina Pectoris, Cluster Headache, Heart Rate, Hypertension, Paroxysmal Supraventricular Tachycardia (PSVT), Supra-ventricular Tachyarrhythmias, Unstable Angina Pectoris, Vasospastic Angina
Associated Therapies
-

Bioequivalence Study Of Verapamil

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-04-29
Last Posted Date
2009-07-08
Lead Sponsor
Pfizer
Target Recruit Count
79
Registration Number
NCT00668967
Locations
🇺🇸

Pfizer Investigational Site, New Haven, Connecticut, United States

Drug Discrimination in Methadone-Maintained Humans Study 1

First Posted Date
2008-01-15
Last Posted Date
2011-03-11
Lead Sponsor
University of Arkansas
Target Recruit Count
40
Registration Number
NCT00593463
Locations
🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Pharmacotherapy of Treatment-Resistant Mania

First Posted Date
2007-08-21
Last Posted Date
2011-02-25
Lead Sponsor
University of Pittsburgh
Target Recruit Count
45
Registration Number
NCT00518947
Locations
🇺🇸

University of Pittsburgh, Pittsburgh, Pennsylvania, United States

Therapy With Verapamil or Carvedilol in Chronic Heart Failure

Phase 4
Conditions
First Posted Date
2006-09-11
Last Posted Date
2006-09-11
Lead Sponsor
Medical University of Silesia
Target Recruit Count
100
Registration Number
NCT00374465
Locations
🇵🇱

Silesian Centre for Heart Disease, 3rd Department of Cardiology, Zabrze, Szpitalna 2 st., Poland

Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic Cardiomyopathy

First Posted Date
2006-07-04
Last Posted Date
2006-10-18
Lead Sponsor
Medical University of Silesia
Target Recruit Count
120
Registration Number
NCT00348530
Locations
🇵🇱

Silesian Center for Heart Disease, IIIrd Department of Cardiology, Silesian Medical University, Zabrze, Poland

RATe Control in Atrial Fibrillation

First Posted Date
2006-04-12
Last Posted Date
2014-05-13
Lead Sponsor
Asker & Baerum Hospital
Target Recruit Count
80
Registration Number
NCT00313157
Locations
🇳🇴

Vestre Viken Hospital Trust, Baerum Hospital, Rud, Akershus, Norway

A Study for Prevention of Kidney Disease in Diabetic Patients (BENEDICT)

First Posted Date
2005-10-10
Last Posted Date
2008-07-15
Lead Sponsor
Abbott
Target Recruit Count
1204
Registration Number
NCT00235014
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