Hyaluronic acid
- Generic Name
- Hyaluronic acid
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C28H44N2O23
- CAS Number
- 9004-61-9
- Unique Ingredient Identifier
- S270N0TRQY
- Background
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not limited to woun...
- Indication
The intra-articular preparations of hyaluronic acid are indicated for knee pain associated with osteoarthritis. Hyaluronic acid is used in cosmetic applications to prevent and reduce the appearance of wrinkles on the face, and as a dermal filler to correct facial imperfections or other imperfections on other parts of the body. It is frequently an ingredient ...
- Associated Conditions
- Actinic Keratosis (AK), Burns, Chronic Skin Ulcers, Conjunctivitis, Dehydration, Dermabrasion, Dermatosis, Dry Eyes, Facial Defect, Interstitial Cystitis, Keratoconjunctivitis, Ocular Irritation, Osteoarthritis (OA), Pain of the knee, Seasonal Allergic Conjunctivitis, Skin Burn, Skin Irritation, Skin fissures, Tissue Adhesions, Varicose Ulcers, Wound, Eye discomfort, Facial fine wrinkling, Sensation of burning in the eyes, Superficial Wounds
- Associated Therapies
- Dermal Filler, Promotion of wound healing, Synovial Fluid Lubrication
Influence of Hyaluronic Acid on Bacillus Calmette-Guérin Local Side Effects
- Conditions
- Interventions
- First Posted Date
- 2014-08-04
- Last Posted Date
- 2015-05-28
- Lead Sponsor
- University of Rome Tor Vergata
- Target Recruit Count
- 30
- Registration Number
- NCT02207608
Effect of Hyaluronic Acid in the Treatment of Periodontal Pockets
- Conditions
- Interventions
- First Posted Date
- 2014-06-23
- Last Posted Date
- 2017-07-27
- Lead Sponsor
- Damascus University
- Target Recruit Count
- 30
- Registration Number
- NCT02170857
- Locations
- 🇸🇾
Department of Periodontics, University of Damascus Dental School, Damascus, Syrian Arab Republic
Treatment of Knee Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells
- Conditions
- Interventions
- First Posted Date
- 2014-04-25
- Last Posted Date
- 2017-10-24
- Target Recruit Count
- 30
- Registration Number
- NCT02123368
- Locations
- 🇪🇸
Orthopaedic and traumatology department. Clínica Universidad de Navarra, Pamplona, Navarra, Spain
🇪🇸Traumatology department. Complejo Hospitalario de Salamanca, Salamanca, Castilla y León, Spain
Daily Activity and Gait Analysis After Viscosupplement Injection Among Hip Osteoarthritis Patients
- First Posted Date
- 2014-03-13
- Last Posted Date
- 2018-08-10
- Lead Sponsor
- Laval University
- Target Recruit Count
- 38
- Registration Number
- NCT02086474
- Locations
- 🇨🇦
Pavillon de l'Éducation Physique et des Sports - Université Laval, Quebec, Canada
Effect Of Plasma Rich In Growth Factors In Knee Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2014-01-17
- Last Posted Date
- 2015-05-05
- Lead Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
- Target Recruit Count
- 96
- Registration Number
- NCT02039531
- Locations
- 🇪🇸
Hospital Universitario Principe de Asturias, Alcala de Henares, Madrid, Spain
Intravesical Instillation of Hyaluronic Acid to Decrease Incidence of Urinary Tract Infection
- First Posted Date
- 2014-01-14
- Last Posted Date
- 2019-04-24
- Lead Sponsor
- Rabin Medical Center
- Registration Number
- NCT02034890
- Locations
- 🇮🇱
Urology department, Rabin Medical Center, Petach Tiqva, Israel
A Comparison Between Sonoguided Injection Corticosteroid and Hyaluronic Acid Injection in Treatment of Trigger Finger
- Conditions
- Interventions
- First Posted Date
- 2013-09-25
- Last Posted Date
- 2014-11-04
- Lead Sponsor
- Taipei Veterans General Hospital, Taiwan
- Target Recruit Count
- 36
- Registration Number
- NCT01950793
- Locations
- 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan
Humectant Activity of a New Formulation of Gynomunal® Vaginalgel
- First Posted Date
- 2013-09-23
- Last Posted Date
- 2013-09-23
- Lead Sponsor
- Derming SRL
- Target Recruit Count
- 28
- Registration Number
- NCT01948583
- Locations
- 🇮🇹
DermIng S.r.l, Monza, MB, Italy
Ultrasonography Guided Subacromial Sodium Hyaluronate Injection in Rotator Cuff Disease
- Conditions
- Interventions
- First Posted Date
- 2012-11-28
- Last Posted Date
- 2012-12-04
- Lead Sponsor
- Isfahan University of Medical Sciences
- Target Recruit Count
- 48
- Registration Number
- NCT01735058
- Locations
- 🇮🇷
Department of Rehabilitation, Alzahra Hospital, Isfahan, Iran, Islamic Republic of
Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells
- Conditions
- Interventions
- First Posted Date
- 2012-04-26
- Last Posted Date
- 2015-10-16
- Lead Sponsor
- Red de Terapia Celular
- Target Recruit Count
- 30
- Registration Number
- NCT01586312
- Locations
- 🇪🇸
Centro Medico Teknon, Barcelona, Spain
🇪🇸Hospital Clinico Universitario, Valladolid, Spain
Drug Development Updates
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