Amiodarone
- Generic Name
- Amiodarone
- Brand Names
- Nexterone, Pacerone
- Drug Type
- Small Molecule
- Chemical Formula
- C25H29I2NO3
- CAS Number
- 1951-25-3
- Unique Ingredient Identifier
- N3RQ532IUT
- Background
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone use s...
- Indication
The FDA approved indications for amiodarone are recurrent ventricular fibrillation (VF) and recurrent hemodynamically unstable ventricular tachycardia (VT). The FDA emphasizes that this drug should only be given in these conditions when they are clinically documented and have not responded to normal therapeutic doses of other antiarrhythmic agents, or when o...
- Associated Conditions
- Atrial Fibrillation, Supraventricular Tachycardia (SVT), Recurrent Ventricular fibrillation, Recurrent hemodynamically unstable Ventricular tachycardia
- Associated Therapies
- -
Amiodarone or Verapamil in COVID-19 Hospitalized Patients With Symptoms
- First Posted Date
- 2020-04-17
- Last Posted Date
- 2021-09-05
- Lead Sponsor
- Nicolaus Copernicus University
- Target Recruit Count
- 804
- Registration Number
- NCT04351763
- Locations
- 🇵🇱
Nicolaus Copernicus University, Bydgoszcz, Poland
Prevention of Post-Operative Cardiac Arrhythmias
- First Posted Date
- 2020-01-21
- Last Posted Date
- 2022-03-15
- Lead Sponsor
- Jeffrey Moak
- Target Recruit Count
- 870
- Registration Number
- NCT04234906
Comparison of Two Strategies for the Management of Atrial Fibrillation After Cardiac Surgery
- First Posted Date
- 2020-01-10
- Last Posted Date
- 2020-01-10
- Lead Sponsor
- University Hospital, Caen
- Target Recruit Count
- 380
- Registration Number
- NCT04223739
- Locations
- 🇫🇷
Caen University Hospital, Caen, Calvados, France
Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABG
- Conditions
- Interventions
- First Posted Date
- 2019-04-05
- Last Posted Date
- 2019-04-05
- Lead Sponsor
- doaa rashwan
- Target Recruit Count
- 48
- Registration Number
- NCT03905759
- Locations
- 🇪🇬
Faculty Of Medicine, Beni-Suef University, Banī Suwayf, Egypt
Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection.
- Conditions
- Interventions
- First Posted Date
- 2019-02-27
- Last Posted Date
- 2019-02-27
- Lead Sponsor
- Sichuan Baili Pharmaceutical Co., Ltd.
- Target Recruit Count
- 756
- Registration Number
- NCT03855826
- Locations
- 🇨🇳
Shenyang Military Region General Hospital, Shenyang, Liaoning, China
Control Versus Liberal Cardiac Frequency in Patients in Sepse With Atrial Fibrillation of High Ventricular Response
- First Posted Date
- 2018-10-23
- Last Posted Date
- 2018-10-23
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 126
- Registration Number
- NCT03715556
- Locations
- 🇧🇷
Instituto do Coração - HMFMUSP, São Paulo, Brazil
Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias
- First Posted Date
- 2018-01-29
- Last Posted Date
- 2019-09-26
- Lead Sponsor
- Groupe Hospitalier Pitie-Salpetriere
- Target Recruit Count
- 80
- Registration Number
- NCT03413150
A Trial Testing Amiodarone in Chagas Cardiomiopathy
- Conditions
- Interventions
- First Posted Date
- 2017-06-21
- Last Posted Date
- 2017-06-21
- Target Recruit Count
- 200
- Registration Number
- NCT03193749
- Locations
- 🇨🇴
Fundación Cardioinfantil - Instituto de Cardiología, Bogotá, Colombia
Catheter Ablation Versus Amiodarone for Therapy of Premature Ventricular Contractions in Patients With Structural Heart Disease
- Conditions
- Interventions
- First Posted Date
- 2016-10-05
- Last Posted Date
- 2021-07-22
- Lead Sponsor
- University of Leipzig
- Target Recruit Count
- 80
- Registration Number
- NCT02924285
- Locations
- 🇩🇪
Heart Center Leipzig, Leipzig, Germany
Amiodarone and N-Acetylcysteine or Amiodarone Alone for Preventing Atrial Fibrillation After Thoracic Surgery
- Conditions
- Interventions
- First Posted Date
- 2016-04-25
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 184
- Registration Number
- NCT02750319
- Locations
- 🇺🇸
Memorial Sloan Kettering Basking Ridge (Consent only), Basking Ridge, New Jersey, United States
🇺🇸University of Washington School of Medicine in St. Louis, Saint Louis, Missouri, United States
🇺🇸Memorial Sloan Kettering Bergen (Consent only), Montvale, New Jersey, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.