Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorp...
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting
- Conditions
- Interventions
- First Posted Date
- 2024-05-13
- Last Posted Date
- 2024-10-08
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 252
- Registration Number
- NCT06411665
- Locations
- 🇨🇳
Dong-Xin Wang, Beijing, China
Oliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid Study
- Conditions
- Interventions
- First Posted Date
- 2024-05-10
- Last Posted Date
- 2024-05-17
- Lead Sponsor
- Tongji Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT06409689
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery
- First Posted Date
- 2024-04-29
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 40
- Registration Number
- NCT06387303
- Locations
- 🇺🇸
University of Virginia, Charlottesville, Virginia, United States
Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2024-04-03
- Last Posted Date
- 2024-04-22
- Lead Sponsor
- Dalin Tzu Chi General Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT06344169
Analgesic Efficacy of Mid-Transverse Process to Pleura (MTP) Block and Intrathecal Morphine in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion
- Conditions
- Interventions
- First Posted Date
- 2024-03-26
- Last Posted Date
- 2024-03-29
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 40
- Registration Number
- NCT06331143
- Locations
- 🇪🇬
Tanta University, Tanta, ElGharbia, Egypt
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
- Conditions
- Interventions
- First Posted Date
- 2024-03-25
- Last Posted Date
- 2024-05-14
- Lead Sponsor
- Boston Children's Hospital
- Target Recruit Count
- 58
- Registration Number
- NCT06326983
- Locations
- 🇺🇸
Boston Children's Hospital, Waltham, Massachusetts, United States
Intrathecal Non-preservative-free Morphine With Bupivacaine Versus Intrathecal Bupivacaine Alone for Analgesia in Unilateral Inguinal Hernia Repair Surgeries
- First Posted Date
- 2024-03-20
- Last Posted Date
- 2024-07-23
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 50
- Registration Number
- NCT06319859
- Locations
- 🇪🇬
Kasr Alaini hospital, Cairo, Egypt
Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department
- Conditions
- Interventions
- First Posted Date
- 2024-03-18
- Last Posted Date
- 2024-03-18
- Lead Sponsor
- Oman Medical Speciality Board
- Target Recruit Count
- 226
- Registration Number
- NCT06315920
Clinical Study to Evaluate Cannabidiol Liver Enzyme Elevations and Drug Interactions
- Conditions
- Interventions
- First Posted Date
- 2024-01-05
- Last Posted Date
- 2024-04-12
- Lead Sponsor
- Food and Drug Administration (FDA)
- Target Recruit Count
- 240
- Registration Number
- NCT06192589
- Locations
- 🇺🇸
Spaulding Clinical Research, West Bend, Wisconsin, United States
Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone
- First Posted Date
- 2023-12-29
- Last Posted Date
- 2024-03-25
- Lead Sponsor
- Murdoch Childrens Research Institute
- Target Recruit Count
- 690
- Registration Number
- NCT06186141
- Locations
- 🇦🇺
The Royal Children's Hospital, Melbourne, Victoria, Australia
Drug Development Updates
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