MedPath

Zanzalintinib

Generic Name
Zanzalintinib
Drug Type
Small Molecule
Chemical Formula
C29H25FN4O5
CAS Number
2367004-54-2
Unique Ingredient Identifier
KC2JC2ZA04

Study of XL092 in Combination With Immuno-Oncology Agents in Subjects With Solid Tumors

Phase 1
Active, not recruiting
Conditions
Non-small Cell Lung Cancer
Metastatic Castration-resistant Prostate Cancer
Colorectal Cancer
Urothelial Carcinoma
Hepatocellular Carcinoma
Head and Neck Squamous Cell Carcinoma
Renal Cell Carcinoma
Solid Tumor
Interventions
First Posted Date
2022-01-04
Last Posted Date
2025-04-02
Lead Sponsor
Exelixis
Target Recruit Count
1274
Registration Number
NCT05176483
Locations
🇺🇸

Exelixis Clinical Site #70, Tyler, Texas, United States

🇺🇸

Exelixis Clinical Site #66, Charlottesville, Virginia, United States

🇺🇸

Exelixis Clinical Site #33, Milwaukee, Wisconsin, United States

and more 119 locations

A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors

Phase 1
Active, not recruiting
Conditions
Renal Cell Carcinoma
Metastatic Castration-resistant Prostate Cancer
Colorectal Cancer
Neoplasm Malignant
Hormone Receptor Positive Breast Carcinoma
Interventions
First Posted Date
2019-02-19
Last Posted Date
2024-11-19
Lead Sponsor
Exelixis
Target Recruit Count
325
Registration Number
NCT03845166
Locations
🇺🇸

Exelixis Clinical Site #84, Los Angeles, California, United States

🇺🇸

Exelixis Clinical Site #71, Stanford, California, United States

🇺🇸

Exelixis Clinical Site #85, Bronx, New York, United States

and more 82 locations

A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Small Cell Lung Cancer)

First Posted Date
2017-11-09
Last Posted Date
2025-05-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
314
Registration Number
NCT03337698
Locations
🇺🇸

Christiana Care Health Services, Newark, Delaware, United States

🇺🇸

Comprehensive Cancer Centers of Nevada (CCCN) - Central Valley, Las Vegas, Nevada, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

and more 29 locations
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