Fluticasone propionate

Generic Name
Fluticasone propionate
Brand Names
Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
Drug Type
Small Molecule
Chemical Formula
C25H31F3O5S
CAS Number
80474-14-2
Unique Ingredient Identifier
O2GMZ0LF5W
Background

Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.

Indication

Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.

Associated Conditions
Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
Associated Therapies
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A Study To Determine Effects Of Fluticasone Propionate On Sputum Neutrophils After Inhaled Lipopolysaccharide Challenge In Volunteers

First Posted Date
2011-06-02
Last Posted Date
2012-02-13
Lead Sponsor
Pfizer
Target Recruit Count
17
Registration Number
NCT01364519
Locations
🇬🇧

Pfizer Investigational Site, London, United Kingdom

Targeted Therapy of Bronchiolitis Obliterans Syndrome

First Posted Date
2011-03-03
Last Posted Date
2017-10-04
Lead Sponsor
Stephanie Lee
Target Recruit Count
36
Registration Number
NCT01307462
Locations
🇺🇸

Stanford University, Stanford, California, United States

🇺🇸

Mayo Clinic - Scottsdale, Scottsdale, Arizona, United States

🇺🇸

National Cancer Institute Experimental Transplantation & Immunology Branch, Bethesda, Maryland, United States

and more 8 locations

Real-world Effectiveness and Cost-effectiveness of Qvar Versus FP, a US Study

First Posted Date
2011-02-01
Last Posted Date
2013-08-05
Lead Sponsor
Research in Real-Life Ltd
Target Recruit Count
82903
Registration Number
NCT01287351
Locations
🇬🇧

Research in Real Life, Cawston, Norfolk, United Kingdom

Effects of Intranasal Corticosteroid and Montelukast On Nasal Allergen Challenges*

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-11-15
Last Posted Date
2012-10-10
Lead Sponsor
Creighton University
Target Recruit Count
60
Registration Number
NCT01240889
Locations
🇺🇸

Creighton University Medical Center, Omaha, Nebraska, United States

Interactive Acute Smooth Muscle Effects of Salmeterol and Fluticasone in the Airway

First Posted Date
2010-11-01
Last Posted Date
2016-06-30
Lead Sponsor
University of Miami
Target Recruit Count
14
Registration Number
NCT01231230

Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-10-07
Last Posted Date
2016-06-29
Lead Sponsor
University of Miami
Target Recruit Count
32
Registration Number
NCT01216735
Locations
🇺🇸

Human Research Laboratory - University of Miami, Miami, Florida, United States

A Study Comparative of Formoterol/Fluticasone Foraseq® and Fluticasone in Asthma Patients

First Posted Date
2010-09-15
Last Posted Date
2015-06-18
Lead Sponsor
Eurofarma Laboratorios S.A.
Target Recruit Count
222
Registration Number
NCT01202084
Locations
🇧🇷

IMA Brasil - Instituto de Pesquisa Clínica e Medicina Avançada, São Paulo, Brazil

Single Dose Pharmacokinetics of Intranasal Fluticasone Delivered by a Fixed Combination With Azelastine (MP29 02) in Comparison to Two Different Fluticasone Nasal Sprays

First Posted Date
2010-09-03
Last Posted Date
2022-02-07
Lead Sponsor
MEDA Pharma GmbH & Co. KG
Target Recruit Count
30
Registration Number
NCT01194622
Locations
🇩🇪

ClinPharmCologne, Cologne, NRW, Germany

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