Fluticasone propionate
- Generic Name
- Fluticasone propionate
- Brand Names
- Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
- Drug Type
- Small Molecule
- Chemical Formula
- C25H31F3O5S
- CAS Number
- 80474-14-2
- Unique Ingredient Identifier
- O2GMZ0LF5W
- Background
Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.
- Indication
Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.
- Associated Conditions
- Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
- Associated Therapies
- -
Impact of Fluticasone and Salmeterol on Airway Dendritic Cells (DCs) in Smokers
- Conditions
- Interventions
- First Posted Date
- 2009-05-25
- Last Posted Date
- 2010-01-13
- Lead Sponsor
- University of Rostock
- Target Recruit Count
- 45
- Registration Number
- NCT00908362
- Locations
- 🇩🇪
Dep. of Pneumology, University of Rostock, Rostock, Mecklenburg-Vorpommern, Germany
A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
- Conditions
- Interventions
- First Posted Date
- 2009-04-17
- Last Posted Date
- 2013-06-24
- Lead Sponsor
- Meda Pharmaceuticals
- Target Recruit Count
- 1791
- Registration Number
- NCT00883168
- Locations
- 🇺🇸
Princeton Center for Clinical Research, Skillman, New Jersey, United States
🇺🇸Clinical Research Institute of Southern Oregon, PC, Medford, Oregon, United States
🇺🇸Allergy and Clinical Immunology Associates, Pittsburgh, Pennsylvania, United States
A Study To Assess The Effect Of PF-03526299 On Lung Function Following An Allergen Challenge In Asthmatic Subjects
- Conditions
- Interventions
- First Posted Date
- 2009-04-07
- Last Posted Date
- 2010-09-28
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 29
- Registration Number
- NCT00877539
- Locations
- 🇬🇧
Pfizer Investigational Site, Manchester, United Kingdom
Study of Biomarkers of Airway Inflammation (0000-128)
- First Posted Date
- 2009-03-26
- Last Posted Date
- 2015-07-23
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 22
- Registration Number
- NCT00869596
A Randomised, Double Blind, Placebo Controlled, 4 Period, Incomplete Block, Crossover Study Assessing the Dose-response Curve of Fluticasone Propionate in an Antigen Challenge Chamber
- Conditions
- Interventions
- First Posted Date
- 2009-02-23
- Last Posted Date
- 2012-09-24
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 59
- Registration Number
- NCT00848965
- Locations
- 🇦🇹
GSK Investigational Site, Vienna, Austria
Azelastine Fluticasone Combination vs. Fluticasone
- Conditions
- Interventions
- First Posted Date
- 2009-02-18
- Last Posted Date
- 2012-06-12
- Lead Sponsor
- University of Dundee
- Registration Number
- NCT00845598
- Locations
- 🇬🇧
Ninewells Hospital and Medical School, Dundee, United Kingdom
🇬🇧Perth Royal Infirmary, Perth, United Kingdom
Efficacy and Safety Study of GSK679586 in Patients With Severe Asthma
- Conditions
- Interventions
- First Posted Date
- 2009-02-13
- Last Posted Date
- 2017-12-12
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 198
- Registration Number
- NCT00843193
- Locations
- 🇬🇧
GSK Investigational Site, Nottingham, United Kingdom
Fluticasone/Salmeterol (FP/SM) Versus Double the Dose Fluticasone (FP) in Patients With Mild to Moderate Asthma
- First Posted Date
- 2009-01-28
- Last Posted Date
- 2019-05-08
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 38
- Registration Number
- NCT00830505
- Locations
- 🇬🇧
Asthma and Allergy Research Group, Dundee, Angus, United Kingdom
Additive Effects of QVAR to (Seretide) on Surrogate Markers of Airway Inflammation in Refractory Asthma
- First Posted Date
- 2009-01-27
- Last Posted Date
- 2019-04-12
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 15
- Registration Number
- NCT00829257
- Locations
- 🇬🇧
Asthma and Allergy Research Group, Ninewells Hospital and Medical School, Dundee, Scotland, United Kingdom
Efficacy, Safety and Pharmacokinetics of QAV680 in Asthma Patients
- Conditions
- Interventions
- First Posted Date
- 2008-12-24
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Novartis
- Target Recruit Count
- 37
- Registration Number
- NCT00814216
- Locations
- 🇮🇳
Novartis Investigative Site, Mysore, India
🇮🇳Novartis Investigative SIte, Nagpur, India
Drug Development Updates
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