Ibuprofen
- Generic Name
- Ibuprofen
- Brand Names
- Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
- Drug Type
- Small Molecule
- Chemical Formula
- C13H18O2
- CAS Number
- 15687-27-1
- Unique Ingredient Identifier
- WK2XYI10QM
- Background
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...
- Indication
Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...
- Associated Conditions
- Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
- Associated Therapies
- -
A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.
- Conditions
- Interventions
- First Posted Date
- 2021-11-05
- Last Posted Date
- 2023-10-26
- Lead Sponsor
- Heron Therapeutics
- Target Recruit Count
- 90
- Registration Number
- NCT05109312
- Locations
- 🇺🇸
Endeavor Clinical Trials, LLC, San Antonio, Texas, United States
🇺🇸First Surgical Hospital, Bellaire, Texas, United States
🇺🇸Legent Orthopedic Hospital, Carrollton, Texas, United States
Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures
- Conditions
- Interventions
- First Posted Date
- 2021-10-13
- Last Posted Date
- 2024-06-18
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 188
- Registration Number
- NCT05076110
- Locations
- 🇺🇸
Mayo clinic, Rochester, Minnesota, United States
Migraine Abortive Treatment
- Conditions
- First Posted Date
- 2021-09-17
- Last Posted Date
- 2021-09-17
- Lead Sponsor
- Bnai Zion Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT05048914
- Locations
- 🇮🇱
Bnai Zion Medical Center, Haifa, Israel
Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT
- Conditions
- Interventions
- First Posted Date
- 2021-08-18
- Last Posted Date
- 2024-06-21
- Lead Sponsor
- IWK Health Centre
- Target Recruit Count
- 100
- Registration Number
- NCT05011149
- Locations
- 🇨🇦
Stollery Children's Hospital, Edmonton, Alberta, Canada
🇺🇸Children's Hospital of Orange County, Orange, California, United States
🇨🇦British Columbia Women's Hospital, Vancouver, British Columbia, Canada
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures
- First Posted Date
- 2021-08-11
- Last Posted Date
- 2021-10-06
- Lead Sponsor
- Major Extremity Trauma Research Consortium
- Target Recruit Count
- 1000
- Registration Number
- NCT05000281
- Locations
- 🇺🇸
University of Utah, Salt Lake City, Utah, United States
Methadone and Medication Abortion
- First Posted Date
- 2021-06-28
- Last Posted Date
- 2023-01-23
- Lead Sponsor
- Boston Medical Center
- Target Recruit Count
- 4
- Registration Number
- NCT04941443
- Locations
- 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity
- Conditions
- Interventions
- First Posted Date
- 2021-05-10
- Last Posted Date
- 2024-01-17
- Lead Sponsor
- David Chi, MD
- Target Recruit Count
- 215
- Registration Number
- NCT04879823
- Locations
- 🇺🇸
UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸Children's Hospital North Surgery Center, Sewickley, Pennsylvania, United States
Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy
- First Posted Date
- 2021-03-10
- Last Posted Date
- 2024-08-16
- Lead Sponsor
- David Chi, MD
- Target Recruit Count
- 73
- Registration Number
- NCT04791761
- Locations
- 🇺🇸
UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies
- Conditions
- Recurrent Acute LeukemiaRecurrent B Acute Lymphoblastic LeukemiaRecurrent Blastic Plasmacytoid Dendritic Cell NeoplasmRecurrent Chronic Myelogenous Leukemia, BCR-ABL1 PositiveRefractory Chronic Myelogenous Leukemia, BCR-ABL1 PositiveRefractory Hairy Cell LeukemiaRefractory Hematologic MalignancyRefractory Hodgkin LymphomaRefractory T Acute Lymphoblastic LeukemiaSystemic Mastocytosis
- Interventions
- First Posted Date
- 2020-12-23
- Last Posted Date
- 2023-12-20
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 13
- Registration Number
- NCT04681105
- Locations
- 🇺🇸
City of Hope Medical Center, Duarte, California, United States
An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
- Conditions
- Interventions
- First Posted Date
- 2020-11-30
- Last Posted Date
- 2024-08-02
- Lead Sponsor
- Alberta Children's Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT04646967
- Locations
- 🇨🇦
Alberta Children's Hospital, Calgary, Alberta, Canada
Drug Development Updates
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