Fluconazole
- Generic Name
- Fluconazole
- Brand Names
- Diflucan
- Drug Type
- Small Molecule
- Chemical Formula
- C13H12F2N6O
- CAS Number
- 86386-73-4
- Unique Ingredient Identifier
- 8VZV102JFY
- Background
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal dr...
- Indication
Fluconazole can be administered in the treatment of the following fungal infections:
1) Vaginal yeast infections caused by Candida
2) Systemic Candida infections
3) Both esophageal and oropharyngeal candidiasis
4) Cryptococcal meningitis
5) UTI (urinary tract infection) by Candida
6) Peritonitis (inflammation of the peritoneum) caused by Candida
...
- Associated Conditions
- Candida intertrigo, Candida pneumonia, Candida urinary tract infection, Candidemia, Candidiasis, Coccidioidomycosis, Esophageal Candidiasis, Fungal Infections, Fungal peritonitis caused by Candida, Meningitis, Cryptococcal, Oropharyngeal Candidiasis, Peritoneal candidiasis, Pneumonia cryptococcal, Pruritus, Skin Irritation, Systemic Candida Infections caused by Candida, Vaginal Candidiasis, Disseminated Candidiasis
- Associated Therapies
- -
Pharmacokinetic Study of Fluconazole in Premature Infants
- First Posted Date
- 2012-09-12
- Last Posted Date
- 2014-11-19
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT01683760
- Locations
- 🇰🇷
Seoul National University Children's Hospital, Seoul, Korea, Republic of
Diflucan Research For Infant Evaluation Of Antifungal Treatment And Prophylaxis Medication
- First Posted Date
- 2012-09-07
- Last Posted Date
- 2021-07-19
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 30
- Registration Number
- NCT01680458
Safety Study of Fluconazole in Combination With Flucytosine for the Treatment of Early Cryptococcal Infection
- Conditions
- Interventions
- First Posted Date
- 2012-03-23
- Last Posted Date
- 2021-09-29
- Lead Sponsor
- Yale University
- Target Recruit Count
- 6
- Registration Number
- NCT01562132
- Locations
- 🇰🇪
Family AIDS Care and Education Services, Sindo, Nyanza, Kenya
Operational Research for Cryptococcal Antigen Screening
- Conditions
- Interventions
- First Posted Date
- 2012-02-17
- Last Posted Date
- 2020-06-04
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 3049
- Registration Number
- NCT01535469
- Locations
- 🇺🇬
Infectious Disease Institute, Makerere University, Kampala, Uganda
🇺🇬Kampala Capital Council Authority Clinics, Kampala, Uganda
Bioavailability Study of Fluconazole Tablets 200 mg Under Fed Conditions
- First Posted Date
- 2012-01-19
- Last Posted Date
- 2012-01-19
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 15
- Registration Number
- NCT01511757
- Locations
- 🇨🇦
MDS Pharma Services, Cohen street, saint-laurent, montreal (quebec), Canada
Bioavailability Study of Fluconazole Tablets 200 mg Under Fasting Conditions
- First Posted Date
- 2012-01-19
- Last Posted Date
- 2012-01-19
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 17
- Registration Number
- NCT01511770
- Locations
- 🇨🇦
MDS Pharma Services, Cohen street, saint-laurent, montreal (quebec), Canada
Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant
- Conditions
- Interventions
- First Posted Date
- 2012-01-04
- Last Posted Date
- 2024-10-16
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 292
- Registration Number
- NCT01503515
- Locations
- 🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
🇺🇸UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States
🇨🇦Hospital for Sick Children, Toronto, Ontario, Canada
Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder
- Conditions
- Interventions
- First Posted Date
- 2011-05-16
- Last Posted Date
- 2017-06-09
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 45
- Registration Number
- NCT01354314
- Locations
- 🇺🇸
The Johns Hopkins Institute for Clinical and Translational Research, Adult Outpatient Clinical Research Unit, Baltimore, Maryland, United States
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia
- Conditions
- Acute Myeloid LeukemiaAdult Acute Monoblastic LeukemiaAdult Acute Monocytic LeukemiaAdult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Adult Acute Myeloid Leukemia With MaturationAdult Acute Myeloid Leukemia With Minimal DifferentiationAdult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A
- Interventions
- First Posted Date
- 2011-03-03
- Last Posted Date
- 2021-03-30
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 517
- Registration Number
- NCT01307579
- Locations
- 🇺🇸
Valley Children's Hospital, Madera, California, United States
🇺🇸Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States
🇺🇸Children's Hospital Los Angeles, Los Angeles, California, United States
Pharmacokinetics/Pharmacodynamics (PK/PD) of Fluconazole in Children on Extracorporeal Membrane Oxygenation (ECMO)
- First Posted Date
- 2010-07-26
- Last Posted Date
- 2017-11-22
- Lead Sponsor
- Michael Cohen-Wolkowiez
- Target Recruit Count
- 21
- Registration Number
- NCT01169402
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.