Fluconazole
- Generic Name
- Fluconazole
- Brand Names
- Diflucan
- Drug Type
- Small Molecule
- Chemical Formula
- C13H12F2N6O
- CAS Number
- 86386-73-4
- Unique Ingredient Identifier
- 8VZV102JFY
- Background
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal dr...
- Indication
Fluconazole can be administered in the treatment of the following fungal infections:
1) Vaginal yeast infections caused by Candida
2) Systemic Candida infections
3) Both esophageal and oropharyngeal candidiasis
4) Cryptococcal meningitis
5) UTI (urinary tract infection) by Candida
6) Peritonitis (inflammation of the peritoneum) caused by Candida
...
- Associated Conditions
- Candida intertrigo, Candida pneumonia, Candida urinary tract infection, Candidemia, Candidiasis, Coccidioidomycosis, Esophageal Candidiasis, Fungal Infections, Fungal peritonitis caused by Candida, Meningitis, Cryptococcal, Oropharyngeal Candidiasis, Peritoneal candidiasis, Pneumonia cryptococcal, Pruritus, Skin Irritation, Systemic Candida Infections caused by Candida, Vaginal Candidiasis, Disseminated Candidiasis
- Associated Therapies
- -
Relative Bioavailability of Olodaterol and Fluconazole
- Conditions
- Interventions
- First Posted Date
- 2010-06-30
- Last Posted Date
- 2014-06-10
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 35
- Registration Number
- NCT01153724
- Locations
- 🇩🇪
1222.48.1 Boehringer Ingelheim Investigational Site, Berlin, Germany
Effects of Urocortins on Forearm Arterial Blood Flow in Healthy Volunteers (Protocol 3)
- Conditions
- Interventions
- First Posted Date
- 2010-03-31
- Last Posted Date
- 2012-05-15
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 10
- Registration Number
- NCT01096706
- Locations
- 🇬🇧
Wellcome Trust Clinical Research Facility, Royal Infirmary of Edinburgh, Edinburgh, Mid Lothian, United Kingdom
Liver Transplant European Study Into the Prevention of Fungal Infection
- Conditions
- Interventions
- First Posted Date
- 2010-01-28
- Last Posted Date
- 2024-11-18
- Lead Sponsor
- Astellas Pharma Inc
- Target Recruit Count
- 350
- Registration Number
- NCT01058174
Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation
- First Posted Date
- 2009-08-24
- Last Posted Date
- 2018-01-04
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 87
- Registration Number
- NCT00964106
- Locations
- 🇰🇷
GSK Investigational Site, Seoul, Korea, Republic of
Study of Fluconazole in Children With Autism Spectrum Disorder
- First Posted Date
- 2009-07-09
- Last Posted Date
- 2009-07-09
- Lead Sponsor
- The Center for Autism and Related Disorders
- Target Recruit Count
- 50
- Registration Number
- NCT00936182
- Locations
- 🇺🇸
International Child Development Resource Center, Melbourne, Florida, United States
🇺🇸Thoughtful House, Austin, Texas, United States
🇺🇸Center for Autism and Related Disorders, Tarzana, California, United States
High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals
- Conditions
- Interventions
- First Posted Date
- 2009-04-22
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 168
- Registration Number
- NCT00885703
- Locations
- 🇺🇬
Joint Clinical Research Centre (JCRC)/Kampala Clinical Research Site, Kampala, Uganda
🇿🇦Durban International Clinical Research Site CRS, Durban, KwaZulu-Natal, South Africa
🇺🇸University of Southern California CRS, Los Angeles, California, United States
Drug-Drug Interaction (DDI) w/Ketoconazole or Fluconazole
- Conditions
- Interventions
- First Posted Date
- 2009-03-12
- Last Posted Date
- 2011-01-25
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 30
- Registration Number
- NCT00860275
- Locations
- 🇺🇸
Ppd Development, Lp, Austin, Texas, United States
Anidulafungin Versus Fluconazole for the Prevention of Fungal Infections in Liver Transplant Recipients
- Conditions
- Interventions
- First Posted Date
- 2009-02-12
- Last Posted Date
- 2014-12-17
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 200
- Registration Number
- NCT00841971
- Locations
- 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
🇺🇸UCLA Medical Cente, Los Angeles, California, United States
🇺🇸University of Washington Medical Center, Seattle, Washington, United States
Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa
- Conditions
- Interventions
- First Posted Date
- 2009-01-28
- Last Posted Date
- 2016-07-18
- Lead Sponsor
- University of Zimbabwe
- Target Recruit Count
- 54
- Registration Number
- NCT00830856
- Locations
- 🇿🇼
University of Zimbabwe, College of Health Sciences, Harare, Zimbabwe
Safety and Efficacy Study of Posaconazole vs. Fluconazole for Prevention of Invasive Fungal Infection (P05387 AM1)(COMPLETED)
- First Posted Date
- 2008-12-19
- Last Posted Date
- 2017-04-07
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 252
- Registration Number
- NCT00811928
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.