Glimepiride

Generic Name
Glimepiride
Brand Names
Duetact, Tandemact
Drug Type
Small Molecule
Chemical Formula
C24H34N4O5S
CAS Number
93479-97-1
Unique Ingredient Identifier
6KY687524K
Background

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure a...

Indication

Glimepiride is indicated for the management of type 2 diabetes in adults as an adjunct to diet and exercise to improve glycemic control as monotherapy.
...

Associated Conditions
Type 2 Diabetes Mellitus
Associated Therapies
-

A Study to Evaluate ITCA 650 Compared to Glimepiride as Add on Therapy for the Treatment of Type 2 Diabetes

Phase 3
Withdrawn
Conditions
Interventions
First Posted Date
2011-10-20
Last Posted Date
2012-12-25
Lead Sponsor
Intarcia Therapeutics
Registration Number
NCT01455922
Locations
🇺🇸

Intarcia Therapeutics, Inc, Hayward, California, United States

A Study to Evaluate ITCA 650 Compared to Glimepiride for the Treatment of Type 2 Diabetes

Phase 3
Withdrawn
Conditions
Interventions
First Posted Date
2011-10-20
Last Posted Date
2012-12-25
Lead Sponsor
Intarcia Therapeutics
Registration Number
NCT01455883
Locations
🇺🇸

Intarcia Therapeutics, Inc, Hayward, California, United States

An Efficacy and Safety Study of Fixed-dose Rosiglitazone/Glimepiride to Treat Chinese Type 2 Diabetes Patients

First Posted Date
2011-10-17
Last Posted Date
2012-03-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
86
Registration Number
NCT01453049
Locations
🇨🇳

GSK Investigational Site, Wuhan, China

Liraglutide and Heart Failure in Type 2 Diabetes

First Posted Date
2011-08-30
Last Posted Date
2016-09-01
Lead Sponsor
Thomas Nystrom
Target Recruit Count
62
Registration Number
NCT01425580
Locations
🇸🇪

Karolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden

🇸🇪

Karolinska Institutet, Division of Internal Medicine Södersjukhuset AB, Stockholm, Sweden

A Study in Patients With Type 2 Diabetes

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2011-08-03
Last Posted Date
2011-08-25
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
240
Registration Number
NCT01408095
Locations
🇪🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Sevilla, Spain

Effects of Sitagliptin on Type 2 Diabetes Mellitus Patients on Treatment With Metformin and Insulin

First Posted Date
2011-04-26
Last Posted Date
2014-05-30
Lead Sponsor
Jothydev's Diabetes and Research Centre
Target Recruit Count
440
Registration Number
NCT01341717
Locations
🇮🇳

Jothydev's Diabetes and Research Center, Thiruvananthapuram, Kerala, India

Efficacy and Safety of Alogliptin Used in Combination With Sulfonylurea in Participants With Type 2 Diabetes in Japan

First Posted Date
2011-03-18
Last Posted Date
2012-02-03
Lead Sponsor
Takeda
Target Recruit Count
312
Registration Number
NCT01318083

Drug-drug Interaction Study With ASP1941 and Glimepiride

Phase 1
Completed
Conditions
First Posted Date
2011-02-23
Last Posted Date
2011-02-23
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
52
Registration Number
NCT01302158

Vildagliptin Glycemic Profiles Assessment Using a Continuous Glucose Monitoring Device.

First Posted Date
2010-12-17
Last Posted Date
2016-11-18
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT01262586
Locations
🇩🇪

Novartis Investigative Site, Mainz, Germany

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