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Pseudoephedrine

Generic Name
Pseudoephedrine
Brand Names
Advil Cold and Sinus, Alavert D, Aleve-D, Allegra-D, Aller-tec D, Allerclear, Bromfed DM, Cheratussin Dac, Clarinex-D, Claritin-D, Codar D, Covan, Entex T, Lodrane D, Mar-cof BP, Mucinex D, Nexafed, Pseudodine C, Rescon Tablets, Semprex-D, Stahist Ad Liquid, Sudafed, Sudafed Sinus & Pain, Sudogest, Triacin-C, Tusnel C, Wal Zyr D, Wal-act, Wal-itin D, Wal-phed, Zephrex-D, Zyrtec-D
Drug Type
Small Molecule
Chemical Formula
C10H15NO
CAS Number
90-82-4
Unique Ingredient Identifier
7CUC9DDI9F
Background

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described in dogs in 1927.

Indication

Pseudoephedrine is a sympathomimetic amine used for its decongestant activity.

Associated Conditions
Allergic Reaction, Allergic Rhinitis (AR), Common Cold, Common Cold Associated With Cough, Cough, Cough caused by Common Cold, Eye allergy, Fever, Flu caused by Influenza, Headache, Irritative cough, Nasal Allergies, Nasal Congestion, Nasal Congestion caused by Common Cold, Pain, Perennial Allergy, Priapism, Respiratory Allergy, Rhinorrhoea, Seasonal Allergic Rhinitis, Seasonal Allergies, Sinus Congestion, Sinusitis, Sneezing, Sore Throat, Symptoms of Acute Bronchitis Accompanied by Coughing, Throat irritation, Upper Respiratory Tract Infection, Upper respiratory tract congestion, Upper respiratory tract signs and symptoms, Cold or flu syndrome, Dry cough, Minor aches and pains, Sinus pain, Watery itchy eyes
Associated Therapies
Airway secretion clearance therapy

Preventing Frequent Sinus Infections in HIV-Infected Patients

Phase 2
Withdrawn
Conditions
HIV Infections
Sinusitis
First Posted Date
2001-08-31
Last Posted Date
2021-10-28
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Registration Number
NCT00000752
Locations
🇺🇸

Univ of California / San Diego Treatment Ctr, San Diego, California, United States

🇺🇸

Thomas Jefferson Univ Hosp, Philadelphia, Pennsylvania, United States

🇺🇸

Stanford at Kaiser / Kaiser Permanente Med Ctr, San Francisco, California, United States

and more 7 locations
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