Cefotaxime

Generic Name: Cefotaxime

Brand Names: Claforan

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₇N_₅O_₇S_₂

CAS Number: 63527-52-6

Unique Ingredient Identifier: N2GI8B1GK7

Background: Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (San...

Indication: Used to treat gonorrhoea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery.

Associated Conditions: Bone and Joint Infections caused by susceptible Bacterial Infections, Central Nervous System Infections caused by susceptible Bacterial Infections, Genitourinary tract infection caused by susceptible Bacterial Infections, Gynaecological infection caused by susceptible bacteria, Intraabdominal Infections caused by susceptible Bacterial Infections, Lower Respiratory Tract Infection (LRTI) caused by susceptible bacteria, Postoperative Wound Infection, Septicemia caused by susceptible Bacterial Infections, Skin and skin-structure infections caused by susceptible bacteria

Associated Therapies: -

Clinical Trials

LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media

Not Applicable

Completed

Conditions: Upper Respiratory Tract Infections

Interventions: Drug: 0.9% NaCl physiological saline Nasal-spraying
Combination Product: LiveSpo Navax®
Drug: Augmentin 500Mg Tablet
Drug: Acetylcysteine
Drug: Xylometazoline Nasal
Drug: Cefotaxime
Drug: Ciprofloxacin

First Posted Date: 2023-04-07

Last Posted Date: 2024-08-22

Lead Sponsor: Anabio R&D

Target Recruit Count: 175

Registration Number: NCT05804123

Locations: 🇻🇳
Thai Binh University of Medicine and Pharmacy, Thai Binh Medical University Hospital and Thai Binh Children's Hospital, Thai Binh, Vietnam

Meropenem vs Cefotaxime as Empirical Treatment of SBP

Phase 4

Conditions: Spontaneous Bacterial Peritonitis

Interventions: Drug: cefotaxime

First Posted Date: 2022-06-22

Last Posted Date: 2022-06-22

Lead Sponsor: Assiut University

Target Recruit Count: 286

Registration Number: NCT05427747

Oral Gemifloxacin Versus Intravenous Cefotaxime in Treatment of Spontaneous Bacterial Peritonitis

Phase 3

Recruiting

Conditions: Spontaneous Bacterial Peritonitis

Interventions: Drug: Gemifloxacin
Drug: Cefotaxime

First Posted Date: 2019-11-19

Last Posted Date: 2019-11-19

Lead Sponsor: Tanta University

Target Recruit Count: 60

Registration Number: NCT04168099

Locations: 🇪🇬
Sherief Abd-Elsalam, Tanta, Egypt

Disturbance of the Intestinal Microbiota by Temocillin vs Cefotaxime in Treatment of Febrile Urinary Tract Infections

Phase 4

Completed

Conditions: Urinary Tract Infections

Interventions: Drug: Temocillin
Drug: Cefotaxime

First Posted Date: 2016-11-09

Last Posted Date: 2019-09-16

Lead Sponsor: Håkan Hanberger

Target Recruit Count: 157

Registration Number: NCT02959957

Locations: 🇸🇪
Centralsjukhuset Kristianstad, Kristianstad, Sweden
🇸🇪
Västmanlands sjukhus i Västerås, Västerås, Sweden
🇸🇪
Karolinska University Hospital, Solna, Stockholm, Sweden

and more 9 locations