MedPath

Indinavir

Generic Name
Indinavir
Brand Names
Crixivan
Drug Type
Small Molecule
Chemical Formula
C36H47N5O4
CAS Number
150378-17-9
Unique Ingredient Identifier
9MG78X43ZT
Background

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]

Indication

Indinavir is an antiretroviral drug for the treatment of HIV infection.

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Associated Therapies
-

A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected Patients

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
500
Registration Number
NCT00001084
Locations
🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium, San Jose, California, United States

🇺🇸

Stanford Univ Med Ctr, Stanford, California, United States

and more 42 locations

A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2012-06-07
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
900
Registration Number
NCT00000919
Locations
🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

Marin County Specialty Clinic, San Rafael, California, United States

🇺🇸

Emory Hemo Comp Evaluation Clinic / East TN Comp Hemo Ctr, Atlanta, Georgia, United States

and more 77 locations

A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2012-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
300
Registration Number
NCT00000918
Locations
🇺🇸

UCLA CARE Ctr, Los Angeles, California, United States

🇺🇸

Univ of Miami School of Medicine, Miami, Florida, United States

🇺🇸

Cook County Hosp, Chicago, Illinois, United States

and more 36 locations

Addition of Efavirenz or Nelfinavir to a Lamivudine/Zidovudine/Indinavir HIV Treatment Regimen

Phase 3
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2012-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
444
Registration Number
NCT00000903
Locations
🇺🇸

USC CRS, Los Angeles, California, United States

🇺🇸

UCLA CARE Center CRS, Los Angeles, California, United States

🇺🇸

Marin County Dept. of Health & Human Services, HIV/AIDS Program & Specialty Clinic, San Rafael, California, United States

and more 47 locations

A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV Infection

First Posted Date
2001-08-31
Last Posted Date
2013-09-06
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
165
Registration Number
NCT00006154
Locations
🇨🇦

Centre Hospitalier de la Universite de Montreal (CHUM), Montreal, Quebec, Canada

🇨🇦

Centre de traitment d'immunodeficience, Montreal, Quebec, Canada

🇨🇦

Viridae Clinical Sciences / University of British Columbia, Vancouver, British Columbia, Canada

and more 1 locations

Treatment With Interleukin-2 (IL-2) Plus Combination Anti-HIV-Drug Therapy (HAART) for Patients Formerly in ACTG 328

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2012-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
110
Registration Number
NCT00000923
Locations
🇺🇸

St. Louis ConnectCare, Infectious Diseases Clinic, St Louis, Missouri, United States

🇺🇸

Harbor-UCLA Med. Ctr. CRS, Torrance, California, United States

🇺🇸

Case CRS, Cleveland, Ohio, United States

and more 9 locations

Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination With Nucleoside Analogs: A Rollover Study for ACTG 320

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-10-28
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
440
Registration Number
NCT00000885
Locations
🇺🇸

Johns Hopkins Hosp, Baltimore, Maryland, United States

🇺🇸

Division of Inf Diseases/ Indiana Univ Hosp, Indianapolis, Indiana, United States

🇺🇸

Boston Med Ctr, Boston, Massachusetts, United States

and more 50 locations

A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS

Phase 2
Completed
Conditions
Mycobacterium Avium-intracellulare Infection
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
246
Registration Number
NCT00001058
Locations
🇺🇸

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis, Indiana, United States

🇺🇸

Methodist Hosp. of Indiana, Indianapolis, Indiana, United States

🇺🇸

Harbor-UCLA Med. Ctr. CRS, Torrance, California, United States

and more 31 locations

A Study of Abacavir Plus Indinavir Sulfate Plus Efavirenz in HIV-Infected Patients

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
300
Registration Number
NCT00001086
Locations
🇺🇸

Johns Hopkins Hosp, Baltimore, Maryland, United States

🇺🇸

Stanford Univ Med Ctr, Stanford, California, United States

🇺🇸

Stanford at Kaiser / Kaiser Permanente Med Ctr, San Francisco, California, United States

and more 53 locations

Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2012-11-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
76
Registration Number
NCT00016601
Locations
🇺🇸

Univ of North Carolina, Chapel Hill, North Carolina, United States

🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

Indiana Univ Hosp, Indianapolis, Indiana, United States

and more 29 locations
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