MedPath

Indinavir

Generic Name
Indinavir
Brand Names
Crixivan
Drug Type
Small Molecule
Chemical Formula
C36H47N5O4
CAS Number
150378-17-9
Unique Ingredient Identifier
9MG78X43ZT
Background

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]

Indication

Indinavir is an antiretroviral drug for the treatment of HIV infection.

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Associated Therapies
-

A Study of the Effectiveness of Different Anti-HIV Treatments in HIV-Positive Individuals Who Have Been on a Protease Inhibitor-Containing Drug Regimen for at Least 16 Weeks

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
800
Registration Number
NCT00000914
Locations
🇺🇸

North Jersey Community Research Initiative, Newark, New Jersey, United States

🇺🇸

Community Consortium / UCSF, San Francisco, California, United States

🇺🇸

AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States

and more 12 locations

A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients

Not Applicable
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT00000896
Locations
🇺🇸

Ucsd, Avrc Crs, San Diego, California, United States

🇺🇸

University of Colorado Hospital CRS, Aurora, Colorado, United States

🇺🇸

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis, Indiana, United States

The Effectiveness of GM-CSF in HIV-Positive Patients Who Are Also Receiving Anti-HIV Therapy

Phase 2
Completed
Conditions
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
108
Registration Number
NCT00000850
Locations
🇺🇸

UCLA CARE Ctr, Los Angeles, California, United States

🇺🇸

Marin County Specialty Clinic, San Rafael, California, United States

🇺🇸

Rush Presbyterian - Saint Luke's Med Ctr, Chicago, Illinois, United States

and more 36 locations

A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas

Phase 2
Completed
Conditions
Ewing's Sarcoma
Rhabdomyosarcoma
Interventions
Biological: therapeutic autologous dendritic cells
Drug: indinavir sulfate
Procedure: peripheral blood stem cell transplantation
First Posted Date
1999-11-04
Last Posted Date
2012-06-15
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
42
Registration Number
NCT00001566
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection

Phase 1
Completed
Conditions
HIV Infection
First Posted Date
1999-11-04
Last Posted Date
2017-07-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
42
Registration Number
NCT00001644
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

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