Calcitriol
- Generic Name
- Calcitriol
- Brand Names
- Rocaltrol, Vectical
- Drug Type
- Small Molecule
- Chemical Formula
- C27H44O3
- CAS Number
- 32222-06-3
- Unique Ingredient Identifier
- FXC9231JVH
- Background
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D, 1,25-dihydroxyvitamin D. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to Vitamin D3 (vita...
- Indication
Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or...
- Associated Conditions
- Hypocalcemia, Mild to Moderate Plaque Psoriasis, Osteodystrophy, Secondary Hyperparathyroidism (SHPT), Vitamin D Resistant Rickets
- Associated Therapies
- -
Vitamin D for the Treatment of Severe Asthma
- First Posted Date
- 2008-07-09
- Last Posted Date
- 2009-08-13
- Lead Sponsor
- Kantonsspital Baselland Bruderholz
- Target Recruit Count
- 20
- Registration Number
- NCT00712205
- Locations
- 🇨🇭
Department of Medicine, Bruderholz, Baselland, Switzerland
Calcitriol in Preventing Lung Cancer in Smokers and Former Smokers at High Risk of Lung Cancer
- Conditions
- Interventions
- First Posted Date
- 2008-06-05
- Last Posted Date
- 2018-06-04
- Lead Sponsor
- Roswell Park Cancer Institute
- Target Recruit Count
- 16
- Registration Number
- NCT00690924
- Locations
- 🇺🇸
Roswell Park Cancer Institute, Buffalo, New York, United States
Efficacy and Safety of Paricalcitol on the Treatment of Secondary Hyperparathyroidism in Calcitriol Resistant Dialysis Subjects
- Conditions
- Interventions
- First Posted Date
- 2008-04-23
- Last Posted Date
- 2012-01-20
- Lead Sponsor
- Abbott
- Target Recruit Count
- 13
- Registration Number
- NCT00664430
- Locations
- 🇧🇷
Site Reference ID/Investigator# 7118, Sao Paulo, Brazil
🇧🇷Site Reference ID/Investigator# 7114, Sao Paulo, Brazil
Teriparatide (Forteo) in the Treatment of Patients With Postoperative Hypocalcemia
- Conditions
- Interventions
- First Posted Date
- 2008-02-26
- Last Posted Date
- 2012-12-06
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 7
- Registration Number
- NCT00623974
- Locations
- 🇺🇸
UT MD Anderson Cancer Center, Houston, Texas, United States
Bioequivalency Study of Calcitriol Tablets Under Fasting Conditions
- Conditions
- First Posted Date
- 2008-01-28
- Last Posted Date
- 2018-01-23
- Lead Sponsor
- Roxane Laboratories
- Target Recruit Count
- 36
- Registration Number
- NCT00601328
- Locations
- 🇺🇸
Bio-Kinetic Clinical Applications, Inc., Springfield, Missouri, United States
Effects of Vitamin D on Renin Expression in Hypertensive Patients
- Conditions
- Interventions
- First Posted Date
- 2008-01-03
- Last Posted Date
- 2016-05-27
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 12
- Registration Number
- NCT00585442
- Locations
- 🇺🇸
University of Utah, Salt Lake City, Utah, United States
The Efficacy and Safety of Calcitriol for the Treatment of Lupus Nephritis and Persistent Proteinuria
- Conditions
- Interventions
- First Posted Date
- 2007-07-30
- Last Posted Date
- 2015-08-04
- Lead Sponsor
- Chinese University of Hong Kong
- Registration Number
- NCT00508898
Vitamin D and Blood Pressure
- Conditions
- Interventions
- First Posted Date
- 2007-04-12
- Last Posted Date
- 2014-01-08
- Lead Sponsor
- Atlanta VA Medical Center
- Registration Number
- NCT00459563
- Locations
- 🇺🇸
VAMC, Decatur, Georgia, United States
Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption
- First Posted Date
- 2007-01-29
- Last Posted Date
- 2013-02-04
- Lead Sponsor
- Atlanta VA Medical Center
- Target Recruit Count
- 9
- Registration Number
- NCT00427804
- Locations
- 🇺🇸
Atlanta VAMC, Atlanta, Georgia, United States
A Phase II Trial of Calcitriol and Naproxen in Patients With Recurrent Prostate Cancer
- Conditions
- First Posted Date
- 2006-10-03
- Last Posted Date
- 2013-01-28
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 20
- Registration Number
- NCT00383487
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.